ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2021
The therapeutic mechanism of epilepsy seizures in different target areas: Research on a theoretical model.
Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
backgroundThe selection of optimal target areas in the surgical treatment of epilepsy is always a difficult problem in medicine.
objectiveWe employed a theoretical calculation model to explore the control mechanism of seizures by an external voltage stimulus acting in different nerve nuclei.
methodsTheoretical analysis and numerical simulation were combined.
resultsThe globus pallidus, excitatory pyramidal neurons, striatal D1 neurons, thalamic reticular nucleus and specific relay nuclei were selected, we analyzed that the electrical stimulation has different effects in these target areas.
conclusionsThe data selected were reasonable in study, the results may give a theoretical support for similar studies in clinical.
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