Evidence map›Paper›PMID 33682631›Full record

ArticleLeukemia & lymphoma2021

Comparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice.

Karthik Ravi, Andrea Franson, Morgan J Homan, Holly Roberts, Manjunath P Pai, Zachary Miklja, Miao He, Bo Wen, Lydia L Benitez, Anthony J Perissinotti and 3 more

Open access · greenAbstract readLetter
In one paragraph

Article in Leukemia & lymphoma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Accelerated-phase CML: de novo and transformed.Hematology. American Society of Hematology. Education Program · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Karthik RaviDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Andrea FransonDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Morgan J HomanUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Holly RobertsDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Manjunath P PaiUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Zachary MikljaMedical College of Wisconsin, Wauwatosa, WI, USA.
Miao HeUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Bo WenUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Lydia L BenitezUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Anthony J PerissinottiUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
Dale L BixbyDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Carl KoschmannDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Bernard L MariniUniversity of Michigan College of Pharmacy, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USMedical College of Wisconsin · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Scott Michael Schuetze · 1988 to 2026
$178.2M
NCI NIH HHS P30 CA046592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood-Brain BarrierPyridazinesAnimalsDasatinibImidazolesMiceProtein Kinase InhibitorsDasatinibImidazolesponatinibProtein Kinase InhibitorsPyridazines

Identifiers

PMID33682631
PMCPMC8855457
OpenAlexW3133746943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.