ArticleEmerging microbes & infections2021
Maternal hepatitis B e antigen can be an indicator for antiviral prophylaxis of perinatal transmission of hepatitis B virus.
Article in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Real-world efficacy of comprehensive measures against mother-to-child transmission of HBV in south-eastern Jiangsu, China.BMC infectious diseases · 2026Article
- Hepatitis B Virus e Antigen in Mother-to-Child Transmission and Clinical Management of Hepatitis B.Viruses · 2025Review
- A Multi-Regional Epidemiological Evaluation on Post-vaccination Serological Testing in Prevention of Vertical Transmission of Hepatitis B Virus - 10 Counties, 5 Provinces, China, 2019-2024.China CDC weekly · 2025Article
- Elective cesarean section and bottle-feeding do not reduce infection of hepatitis B in infants of high viremic mothers: a retrospective study.BMC pregnancy and childbirth · 2025Article
- 2024 latest report on hepatitis B virus epidemiology in China: current status, changing trajectory, and challenges.Hepatobiliary surgery and nutrition · 2025Review
- Investigation of Mother-to-Child Transmission of Hepatitis B in Yinchuan, China: Cross-Sectional Survey Study.JMIR public health and surveillance · 2024Article
- Expert Consensus on the Prevention and Treatment of Chronic Hepatitis B in Children.Infectious diseases & immunity · 2024Article
- [Research progress on clinical antiviral treatment of chronic hepatitis B in children].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- Making Elimination of Perinatal Hepatitis B Infection a Reality: The Chinese Contribution.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024Article
- Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China.Nature medicine · 2024Article
- C2729T mutation associated with HBV mother-to-child transmission reduces HBV production via suppressing LHBs expression.Virulence · 2023Article
- Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022).Journal of clinical and translational hepatology · 2023Article
- The relationship of maternal hepatitis B e antigen and response to vaccination of infants born to women with chronic infection.BMC pregnancy and childbirth · 2023Article
- Investigating the relationship between hepatitis B virus infection and postpartum depression in Chinese women: a retrospective cohort study.Frontiers in public health · 2023Article
- [Guidelines for the prevention and treatment of chronic hepatitis B (version 2022)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- A booster hepatitis B vaccine for children with maternal HBsAg positivity before 2 years of age could effectively prevent vaccine breakthrough infections.BMC infectious diseases · 2022Article
- Hepatitis B prevalence in pregnant women in China: Progress and realities.The Lancet regional health. Western Pacific · 2021Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a high-risk factor of perinatal HBV transmission, the potential role of maternal hepatitis B e antigen (HBeAg) to guide antiviral prophylaxis has not yet been fully reported. This large prospective cohort study enrolled 1177 hepatitis B surface antigen (HBsAg)-positive pregnant women without antiviral treatment and their newborns. HBeAg, HBsAg, and viral load in maternal serum collected before delivery were measured. All the newborns were given standard passive-active immunoprophylaxis within 12 h after birth, and post-vaccination serologic testing was performed at 7 (±7d) months of age. The results revealed that 20 of the 1177 infants (1.70%) were immunoprophylaxis failure, and all their mothers were HBeAg positive. Maternal quantitative HBeAg was positively correlated with viral load (
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