SynthesisWestern journal of nursing research2022
Chronic Obstructive Pulmonary Disease Symptom Cluster Composition, Associated Factors, and Methodologies: A Systematic Review.
Synthesis in Western journal of nursing research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05922267 (Comparative Effects of Active Cycle of Breathing Techniques and Slow Expiration With Open Glottis in Lateral Posture in Patients With Chronic Obstructive Pulmonary Disease), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of Active Cycle of Breathing Techniques and Slow Expiration With Open Glottis in Lateral Posture in Patients With Chronic Obstructive Pulmonary Disease
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Symptom Clusters of Chronic Obstructive Pulmonary Disease and Their Correlation With Health-Related Quality of Life: A Systematic Review.Nursing open · 2026Pooled it
- Disability in Older Adults with COPD: Prevalence, Assessment, and Influencing Factors - A Scoping Review.Clinical interventions in aging · 2026Article
- Network Analysis of Symptom Clusters and Core Symptoms in Patients with Type 2 Diabetes Mellitus.Patient preference and adherence · 2026Article
- A longitudinal study on the correlation between symptom clusters and disease-specific health status in older adults with chronic obstructive pulmonary disease during pulmonary rehabilitation.Frontiers in public health · 2026Article
- Article
- Empowering nurses to provide palliative care for COPD patients in a pulmonary department: participatory action research.BMC palliative care · 2025Article
- Association of Patient-Reported Outcome Patterns and Major Clinical Factors with Frailty in Stable COPD.International journal of chronic obstructive pulmonary disease · 2025Article
- Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Self-report of symptom cluster experiences in cancer patient-caregiver dyads.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Article
- Symptom burden and its associations with clinical characteristics in patients with COPD: a clustering approach.ERJ open research · 2024Article
- Exploring the Link between Social Support and Patient-Reported Outcomes in Chronic Obstructive Pulmonary Disease Patients: A Cross-Sectional Study in Primary Care.Healthcare (Basel, Switzerland) · 2024Article
- Symptom clusters, associated factors and health-related quality of life in patients with chronic obstructive pulmonary disease: A structural equation modelling analysis.Journal of clinical nursing · 2023Article
- Synergistic Impact of the Symptom Cluster on Health-Related Quality of Life in Patients With Chronic Obstructive Pulmonary Disease: A Secondary Data Analysis.Clinical nursing research · 2022Article
- Adapting a digital monitoring system for self-management to geriatric COPD rehabilitation: A participatory mixed method study.Digital healthArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review details symptom clusters, their compositions, and associated factors and appraises the methodologies of studies that reported symptom clusters in patients with chronic obstructive pulmonary disease (COPD). Ten studies were eligible for inclusion in this study. Four common symptom clusters were identified. Two theoretical frameworks, four statistical methods, and various symptom assessment tools were used to identify symptom clusters. Factors associated with symptom clusters included demographic, clinical, and biological factors. No studies examined the subjective experiences of symptom clusters. Overall, inconsistencies were identified in the composition of symptom clusters across studies. This may be due to variations in study design, assessment tools, and statistical methods. Future studies should attempt to arrive at a common definition, especially that is theoretically derived, for symptom clusters, standardize the criteria for symptoms for inclusion in the clusters, and focus on patients' subjective experience to inform which clusters are clinically relevant.
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