Evidence map›Paper›PMID 33682033›Full record

SynthesisHeart failure reviews2022

Prognostic value of blood pressure in ambulatory heart failure: a meta-analysis and systematic review. Ambulatory blood pressure predicts heart failure prognosis.

Michael H Lee, Mariela Leda, Tayler Buchan, Abdullah Malik, Alanna Rigobon, Helen Liu, Julian F Daza, Kathleen O'Brien, Madeleine Stein, Nicholas Ng Fat Hing and 6 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Heart failure reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Michael H LeeFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Mariela LedaTed Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada.
Tayler BuchanTed Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada.
Abdullah MalikFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Alanna RigobonFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Helen LiuUniversity of Toronto, Toronto, ON, Canada.
Julian F DazaUniversity of Toronto, Toronto, ON, Canada.
Kathleen O'BrienFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Madeleine SteinColumbia University, New York City, NY, USA.
Nicholas Ng Fat HingFaculty of Medicine, Ottawa University, Ottawa, ON, Canada.
Reed SiemeiniukMcMaster University, Hamilton, ON, Canada.
Nigar SekerciogluMcMaster University, Hamilton, ON, Canada.
Nathan EvaniewSection of Orthopedic Surgery, University of Calgary, Calgary, AB, Canada.
Farid ForoutanTed Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada.
Heather RossTed Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada.
Ana Carolina AlbaTed Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada. Carolina.alba@uhn.ca.
University of Toronto · CAMcMaster University · CATed Rogers Centre for Heart Research · CAUniversity Health Network · CAColumbia University · USUniversity of Calgary · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous primary studies have explored the association between blood pressure (BP) and mortality in ambulatory heart failure (HF) patients reporting varying and contrasting associations. The aim is to determine the pooled BP prognostic value and explore potential reasons for between-study inconsistency. We searched Medline, Cochrane, EMBASE and CINAHL from January 2005 to October 2018 for studies with ≥ 50 events (mortality and/or hospitalization) and included BP in a multivariable model in ambulatory HF patients. We pooled hazard ratios (random effects model) for systolic BP (SBP) or diastolic BP (DBP) effect on mortality and/or hospitalization risk. We used a priori defined sub-group analyses to explore heterogeneity and GRADE approach to assess the certainty of the evidence. Seventy-one eligible articles (239,467 screened) at low to moderate risk of bias included 235,752 participants. Higher SBP was associated with reduced all-cause mortality (HR 0.93, 95%CI 0.91-0.95, I

Indexed as

Heart FailureHypertensionBlood PressureBlood Pressure Monitoring, AmbulatoryHumansPrognosisBlood pressureHeart failureMeta-analysisMortalityPrognosis

Identifiers

PMID33682033
OpenAlexW3135743709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.