Evidence map›Paper›PMID 33681830›Full record

ArticleThe Lancet regional health. Western Pacific2021

Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study.

Henry Surendra, Iqbal Rf Elyazar, Bimandra A Djaafara, Lenny L Ekawati, Kartika Saraswati, Verry Adrian, Widyastuti, Dwi Oktavia, Ngabila Salama, Rosa N Lina and 7 more

Abstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Human genetic factors associated with pneumonia risk, a cue for COVID-19 susceptibility.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
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  19. Determinant Factors of Mortality in Pre-elderly and Elderly Patients With COVID-19 in Jakarta, Indonesia.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Henry SurendraEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Iqbal Rf ElyazarEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Bimandra A DjaafaraEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Lenny L EkawatiEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Kartika SaraswatiEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Verry AdrianJakarta Provincial Health Office, Jakarta, Indonesia.
WidyastutiJakarta Provincial Health Office, Jakarta, Indonesia.
Dwi OktaviaJakarta Provincial Health Office, Jakarta, Indonesia.
Ngabila SalamaJakarta Provincial Health Office, Jakarta, Indonesia.
Rosa N LinaEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Adhi AndriantoEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Karina D LestariEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Erlina BurhanFaculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Anuraj H ShankarEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Guy ThwaitesCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
J Kevin BairdEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.
Raph L HamersEijkman-Oxford Clinical Research Unit, Jakarta, Indonesia.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundData on COVID-19-related mortality and associated factors from low-resource settings are scarce. This study examined clinical characteristics and factors associated with in-hospital mortality of COVID-19 patients in Jakarta, Indonesia, from March 2 to July 31, 2020.

methodsThis retrospective cohort included all hospitalised patients with PCR-confirmed COVID-19 in 55 hospitals. We extracted demographic and clinical data, including hospital outcomes (discharge or death). We used logistic regression to examine factors associated with mortality.

findingsOf 4265 patients with a definitive outcome by July 31, 3768 (88%) were discharged and 497 (12%) died. The median age was 46 years (IQR 32-57), 5% were children, and 31% had >1 comorbidity. Age-specific mortalities were 11% (7/61) for <5 years; 4% (1/23) for 5-9; 2% (3/133) for 10-19; 2% (8/638) for 20-29; 3% (26/755) for 30-39; 7% (61/819) for 40-49; 17% (155/941) for 50-59; 22% (132/611) for 60-69; and 34% (96/284) for ≥70. Risk of death was associated with higher age, male sex; pre-existing hypertension, diabetes, or chronic kidney disease; clinical diagnosis of pneumonia; multiple (>3) symptoms; immediate ICU admission, or intubation. Across all ages, risk of death was higher for patients with >1 comorbidity compared to those without; notably the risk was six-fold increased among patients <50 years (adjusted odds ratio 5.87, 95%CI 3.28-10.52; 27% vs 3% mortality).

interpretationOverall in-hospital mortality was lower than reported in high-income countries, probably due to younger age distribution and fewer comorbidities. Deaths occurred across all ages, with >10% mortality among children <5 years and adults >50 years.

Indexed as

childrencoronavirusCOVID-19IndonesiaMortalitySARS-CoV-2

Identifiers

PMID33681830
PMCPMC7924904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.