Evidence map›Paper›PMID 33681779›Full record

ArticleBMJ neurology open2020

Impact of interhospital transfer on patients undergoing endovascular thrombectomy for acute ischaemic stroke in an Australian setting.

Leon Stephen Edwards, Christopher Blair, Dennis Cordato, Alan McDougall, Nathan Manning, Andrew Cheung, Jason Wenderoth, Cecilia Cappelen-Smith

Abstract read
In one paragraph

Article in BMJ neurology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leon Stephen EdwardsDepartment of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Christopher BlairDepartment of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Dennis CordatoDepartment of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Alan McDougallDepartment of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.
Nathan ManningStroke and Neurology research group, Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia.
Andrew CheungStroke and Neurology research group, Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia.
Jason WenderothStroke and Neurology research group, Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia.
Cecilia Cappelen-SmithDepartment of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of interhospital transfer on the interplay between functional outcome, mortality, reperfusion rates and workflow time metrics in patients undergoing endovascular thrombectomy (EVT) for acute ischaemic stroke due to large vessel occlusion (LVO) in the anterior cerebral circulation. DESIGN SETTING AND

participantsThis is an analysis of a prospective database of consecutive patients undergoing EVT for LVO presenting between January 2017 and December 2018 at a single Australian comprehensive stroke centre (CSC). Patients presented directly or were transferred to the CSC from 21 sites across New South Wales and the Australian Capital Territory.

main outcome measuresThe main outcome measures were rate of good 90-day functional outcome (modified Rankin Scale 0-2), successful reperfusion (Thrombolysis in Cerebral Infarction scale grade 2b or 3), symptomatic intracerebral haemorrhage (sICH) and 90-day mortality. Key workflow time metric milestones were examined.

results154 of 213 (72%) patients were interhospital transfers. There was no significant difference in baseline characteristics including age, National Institutes of Health Stroke Scale score, intravenous thrombolysis administration or procedure time between transferred and direct presenters (all p>0.05). Transferred patients had worse 90-day functional outcome (39.6% vs 61.0%, OR 0.42, 95% CI 0.23 to 0.78), higher mortality (25.3% vs 6.8%, OR 4.66, CI 1.59 to 13.70) and longer stroke onset to treatment (groin puncture) time (298 min vs 205 min, p<0.01). Successful reperfusion rates and sICH were similar between the cohorts (96.8% vs 98.3%, and 7.8% vs 3.4%).

conclusionInterhospital transfer is associated with longer stroke onset to treatment, worse 90-day functional outcome and higher mortality compared with patients presenting directly to the CSC.

Indexed as

cerebrovascularcerebrovascular diseasestroke

Identifiers

PMID33681779
PMCPMC7903172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.