Evidence map›Paper›PMID 33681743›Full record

ArticleEClinicalMedicine2021

Fatal self-injury in the United States, 1999-2018: Unmasking a national mental health crisis.

Ian R H Rockett, Eric D Caine, Aniruddha Banerjee, Bina Ali, Ted Miller, Hilary S Connery, Vijay O Lulla, Kurt B Nolte, G Luke Larkin, Steven Stack and 11 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Unanticipated Changes in Drug Overdose Death Rates in Canada During the Opioid Crisis.International journal of mental health and addiction · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Geographic Disparities in Readmissions for Peripheral Artery Disease in South Carolina.International journal of environmental research and public health · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ian R H RockettDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown, WV, United States.
Eric D CaineDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, United States.
Aniruddha BanerjeeDepartment of Geography, Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana, United States.
Bina AliPacific Institute for Research and Evaluation, Calverton, Maryland, United States.
Ted MillerPacific Institute for Research and Evaluation, Calverton, Maryland, United States.
Hilary S ConneryMcLean Hospital, Belmont, Massachusetts, United States.
Vijay O LullaDepartment of Geography, Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana, United States.
Kurt B NolteDepartment of Pathology and Radiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States.
G Luke LarkinNortheast Ohio Medical University, Rootstown, Ohio, United States.
Steven StackDepartment of Criminal Justice, Wayne State University, Detroit, Michigan, United States.
Brian HendricksDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown, WV, United States.
R Kathryn McHughMcLean Hospital, Belmont, Massachusetts, United States.
Franklin M M WhiteDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Shelly F GreenfieldMcLean Hospital, Belmont, Massachusetts, United States.
Amy S B BohnertDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, Michigan, United States.
Jeralynn S CossmanCollege for Health, Community and Policy, University of Texas-San Antonio, San Antonio, Texas, United States.
Gail D'OnofrioDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, United States.
Lewis S NelsonDepartment of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, United States.
Paul S NestadtDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States.
James H BerryDepartment of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine, Morgantown, West Virginia, United States.
Haomiao JiaDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York, United States.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
NCATS NIH HHS UL1 TR001863NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

backgroundSuicides by any method, plus 'nonsuicide' fatalities from drug self-intoxication (estimated from selected forensically undetermined and 'accidental' deaths), together represent self-injury mortality (SIM)-fatalities due to mental disorders or distress. SIM is especially important to examine given frequent undercounting of suicides amongst drug overdose deaths. We report suicide and SIM trends in the United States of America (US) during 1999-2018, portray interstate rate trends, and examine spatiotemporal (spacetime) diffusion or spread of the drug self-intoxication component of SIM, with attention to potential for differential suicide misclassification.

methodsFor this state-based, cross-sectional, panel time series, we used de-identified manner and underlying cause-of-death data for the 50 states and District of Columbia (DC) from CDC's

findingsThe national annual average percentage change over the observation period in the SIM rate was 4.3% (95% CI: 3.3%, 5.4%;

interpretationDepiction of rising SIM trends across states and major regions unmasks a burgeoning national mental health crisis. Geographic variation is plausibly a partial product of local heterogeneity in toxic drug availability and the quality of medicolegal death investigations. Like COVID-19, the nation will only be able to prevent SIM by responding with collective, comprehensive, systemic approaches. Injury surveillance and prevention, mental health, and societal well-being are poorly served by the continuing segregation of substance use disorders from other mental disorders in clinical medicine and public health practice.

fundingThis study was partially funded by the National Centre for Injury Prevention and Control, US Centers for Disease Control and Prevention (R49CE002093) and the US National Institute on Drug Abuse (1UM1DA049412-01; 1R21DA046521-01A1).

Indexed as

DrugsInjuryMental disordersMental healthMortalityPoisoningPreventionSubstance misuseSuicide

Identifiers

PMID33681743
PMCPMC7910714

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.