Evidence map›Paper›PMID 33681667›Full record

ArticleEpilepsia open2021

Morphometric analysis program: Detection of epileptic foci in young children using an adult normative database: Initial experience.

Ximena Stecher, Valeria Schonstedt, Carla Manterola, Fernando Carreño, Francisco Zamorano, Alvaro Velasquez, Mauricio Castillo

Open access · goldAbstract read
In one paragraph

Article in Epilepsia open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ximena StecherRadiology Department, Clínica Alemana de Santiago, Vitacura, Chile.ORCID https://orcid.org/0000-0002-7962-9519
Valeria SchonstedtRadiology Department, Clínica Alemana de Santiago, Vitacura, Chile.
Carla ManterolaPediatric Department, Clínica Alemana de Santiago, Vitacura, Chile.ORCID https://orcid.org/0000-0003-3394-1010
Fernando CarreñoRadiology Department, Clínica Alemana de Santiago, Vitacura, Chile.
Francisco ZamoranoRadiology Department, Clínica Alemana de Santiago, Vitacura, Chile.
Alvaro VelasquezFacultad de Medicina, Clínica Alemana - Universidad del Desarrollo, Santiago, Chile.
Mauricio CastilloDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA.
Clínica Alemana · CLUniversidad del Desarrollo · CLUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report our initial experience using an adult-template MAP in drug-resistant focal epilepsy in five children with apparently normal MRI. Methods: Patients selected were highly suspicious of harboring focal structural lesions and had negative brain MRI studies. MAP was performed using a locally obtained adult database as a template. Results were reviewed by two neuroradiologists. Pertinence of MAP-positive areas was confirmed by the focal epileptic hypothesis or by pathology when possible ( Results: Five patients aged 19-48 months were studied, all with initial 3T MRI studies interpreted as normal. All had focal epileptic hypothesis with coherence of clinical seizure characterization and electroencephalographic findings. In two patients, histology showed type 1 FCD. Due to the age of our subjects, the junction map always highlighted the subcortical white matter in relationship to maturity differences. FCD was identified as asymmetric U-shaped highlighted regions in the junction map. Significance: FCD is the most frequent pathology reported in pediatric epilepsy surgery series (

Indexed as

Databases, FactualImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultChild, PreschoolDrug Resistant EpilepsyElectroencephalographyFemaleHumansInfantMaleMiddle AgedRetrospective StudiesSeizuresWhite MatterYoung Adultfocal cortical dysplasiaMRI postprocessingnonlesionalpediatricrefractory epilepsy

Identifiers

PMID33681667
PMCPMC7918321
OpenAlexW3110054035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.