Evidence map›Paper›PMID 33681646›Full record

ReviewEpilepsia open2021

Capturing seizures in clinical trials of antiseizure medications for

John J Millichap, Cynthia L Harden, Dennis J Dlugos, Jacqueline A French, Noam N Butterfield, Celene Grayson, Ernesto Aycardi, Simon N Pimstone

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Epilepsia open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

John J MillichapEpilepsy Center and Division of Neurology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-0798-0131
Cynthia L HardenXenon Pharmaceuticals, Inc., Burnaby, British Columbia, Canada.
Dennis J DlugosChildren's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Jacqueline A FrenchDepartment of Neurology NYU Langone School of Medicine, New York, NY, USA.ORCID https://orcid.org/0000-0003-2242-8027
Noam N ButterfieldXenon Pharmaceuticals, Inc., Burnaby, British Columbia, Canada.
Celene GraysonXenon Pharmaceuticals, Inc., Burnaby, British Columbia, Canada.
Ernesto AycardiXenon Pharmaceuticals, Inc., Burnaby, British Columbia, Canada.
Simon N PimstoneXenon Pharmaceuticals, Inc., Burnaby, British Columbia, Canada.
Xenon Pharmaceuticals (Canada) · CAChildren's Hospital of Philadelphia · USNorthwestern University · USNYU Langone Health · USUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Literature review of patients with

Indexed as

SeizuresVideo RecordingBrain DiseasesClinical Trials as TopicDiaries as TopicElectroencephalographyEpileptic SyndromesHumansInfantInfant, NewbornKCNQ2 Potassium ChannelPediatricsProspective StudiesUnited StatesKCNQ2 Potassium ChannelKCNQ2 protein, humanepilepsyKCNQ2seizure diariestonic seizuresvideo‐EEG

Identifiers

PMID33681646
PMCPMC7918316
OpenAlexW3119707510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.