Evidence map›Paper›PMID 33681544›Full record

ArticleCurrent opinion in physiology2021

Rethinking the role of taste processing in insular cortex and forebrain circuits.

John D Boughter, Max Fletcher

Abstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. The S1-insula Circuit Differentially Modulates Alcohol Drinking and Aversive Behavior in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Article
  3. Review
  4. Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  5. Chemosensory tobacco product toxicology part 2: toxicological testing, assays, and state of the science.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Encoding Taste: From Receptors to Perception.Handbook of experimental pharmacology · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John D BoughterDepartment of Anatomy & Neurobiology, University of Tennessee Health Science Center, 855 Monroe Ave., Memphis TN 38163 USA.
Max FletcherDepartment of Anatomy & Neurobiology, University of Tennessee Health Science Center, 855 Monroe Ave., Memphis TN 38163 USA.

Funding

Spatial taste coding in mouse gustatory cortexR01DC016833 · NIDCD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BOUGHTER, JOHN D, FLETCHER, MAX L · 2018 to 2022
$1.9M
NIDCD NIH HHS R01 DC016833
6 · The paper itself

Abstract

Over the years, many approaches towards studying the taste-responsive area of insular cortex have focused on how basic taste information is represented, and how lesions or silencing of this area impact taste-focused behaviors. Here, we review and highlight recent studies that imply that insular cortex does not contain a "primary" taste cortex in the traditional sense. Rather, taste is employed in concert with other internal and external sensory modalities by highly interconnected regions of insular cortex to guide ingestive decision-making, especially in context of estimating risk and reward. In rodent models, this may best be seen in context of foraging behaviors, which require flexibility and are dependent on learning and memory processes.

Indexed as

behaviorcircuitcortexfeedingforagingtaste

Identifiers

PMID33681544
PMCPMC7932132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.