Evidence map›Paper›PMID 33681512›Full record

ArticleJMA journal2019

Coronary Lesions and Systemic Inflammatory Response Syndrome in Kawasaki Disease.

Yutaro Tomobe, Osamu Nomura, Yoshihiko Morikawa, Nobuaki Inoue, Hiroshi Sakakibara, Masaru Miura

Open access · diamondAbstract read
In one paragraph

Article in JMA journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yutaro TomobeDepartment of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Osamu NomuraDivision of Pediatric Emergency Medicine, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Yoshihiko MorikawaClinical Research Support Center, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Nobuaki InoueDivision of Pediatric Emergency Medicine, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Hiroshi SakakibaraDepartment of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Masaru MiuraClinical Research Support Center, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Tokyo Metropolitan Children's Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn patients with Kawasaki disease (KD), who later develop coronary artery lesions (CALs), several inflammatory cytokines are reportedly higher than in patients without CALs. Systemic inflammatory response syndrome (SIRS) is used as a clinical index of hypercytokinemia. The objective of this study was to determine whether SIRS is related to CAL formation.

methodsWe conducted a retrospective cohort study of KD patients admitted to our hospital between July 2012 and July 2015. The subjects were classified into the SIRS or the non-SIRS group based on their vital signs and blood test results. Their initial treatment was determined by their Kobayashi score. We compared the incidence of CALs between the two groups.

resultsOf 357 KD patients, 277 were included in this study and 175 (63.2%) met the SIRS criteria. The incidence of CAL formation at week 1 in the clinical course and at one month after the primary treatment was significantly higher in the SIRS group than in the non-SIRS group (17.7% vs. 7.8%,

conclusionsSIRS can be a risk factor for CAL in the acute phase of KD.

Indexed as

coronary artery lesionKawasaki diseaseKobayashi scoresystemic inflammatory response syndromevital signs

Identifiers

PMID33681512
PMCPMC7930751
OpenAlexW3133853747

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.