Evidence map›Paper›PMID 33681495›Full record

ArticleHeliyon2021

Study of antimicrobial activity of Unani poly herbal toothpaste "

Ayesha Parveen, Qazi Zaid Ahmad, Mohammad Rashid, Aziz Ur Rahman, Sumbul Rehman

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ayesha ParveenDepartment of Saidla (Pharmacy), Faculty of Unani Medicine, India.
Qazi Zaid AhmadDepartment of Saidla (Pharmacy), Faculty of Unani Medicine, India.
Mohammad RashidDepartment of Saidla (Pharmacy), Faculty of Unani Medicine, India.
Aziz Ur RahmanDepartment of Saidla (Pharmacy), Faculty of Unani Medicine, India.
Sumbul RehmanDepartment of Ilmul Advia (Pharmacology), Faculty of Unani Medicine, India.
Regional Research Institute of Unani Medicine · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study was envisioned to develop MATERIALS AND

methodsHerbal extracts based powder was redesigned to toothpaste as per the Pharmacopoeial guidelines and its pharmaceutical evaluation was conceded as per the Indian Government Tooth Paste Specifications. In vitro study was done to evaluate the antibacterial activity by using agar well diffusion method against dental pathogens. Zone of Inhibition was taken as the end parameter against the test pathogens after appropriate incubation period. It was compared with Dimethyl sulphoxide (DMSO) used as solvent (0.01%) as Negative control whereas Ciprofloxacin 5μg/disk (standard antibiotic for gram positive) and Gentamicin 10μg/disk (standard antibiotic for gram negative) were used as Positive control. All the experiment was done as per the Clinical and Laboratory Standards Institute (CLSI) Guidelines in triplicates.

results

conclusionThe developed toothpaste from classical Unani herbal tooth powder will provide the better patient compliance. Moreover its scientific screening which exhibited potential antibacterial activity in controlling pathogenic oral microflora compared to the standard drugs also revalidated the claim of Unani Physicians that the

Indexed as

Antibacterial activitySanoon ZardToothpaste

Identifiers

PMID33681495
PMCPMC7910502
OpenAlexW3129880953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.