Trial reportBioMed research international2021
Gut Microbiota Profile in Adult Patients with Idiopathic Nephrotic Syndrome.
Trial report in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 63 citations in OpenAlex.
- Depletion of gut microbiota alleviates proteinuria in puromycin aminonucleoside-induced nephrosis in rats.Pediatric research · 2026Article
- Gut Microbiome as a Risk Factor for Future CKD.Kidney international reports · 2025Article
- Gut microbiota and ovarian diseases: a new therapeutic perspective.Journal of ovarian research · 2025Review
- Gut microbiota therapy for chronic kidney disease.Frontiers in immunology · 2025Review
- Unraveling the mysteries of the gut-kidney axis: the protective role of traditional Chinese medicine in chronic kidney disease.Frontiers in microbiology · 2025Review
- Alterations of gut microbiota and metabolome are associated with primary nephrotic syndrome in children.BMC microbiology · 2024Article
- Multi-omics landscape of childhood simple obesity: novel insights into pathogenesis and biomarkers discovery.Cell & bioscience · 2024Article
- Metagenomics-Metabolomics Exploration of Three-Way-Crossbreeding Effects on Rumen to Provide Basis for Crossbreeding Improvement of Sheep Microbiome and Metabolome of Sheep.Animals : an open access journal from MDPI · 2024Article
- Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort.Nutrients · 2024Article
- Exploration of the pathogenesis of nephrotic syndrome and traditional Chinese medicine intervention based on gut microbiota.Frontiers in immunology · 2024Review
- The regulation of intestinal flora on host's genes may play an essential role in the development of endometrial hyperplastic processes in yang deficiency individuals.International journal of clinical and experimental pathology · 2024Article
- Effects ofFrontiers in pharmacology · 2024Article
- Causal relationship between the gut microbiota and insomnia: a two-sample Mendelian randomization study.Frontiers in cellular and infection microbiology · 2024Article
- An altered gut microbiome in pre-eclampsia: cause or consequence.Frontiers in cellular and infection microbiology · 2024Review
- Correlation between gut microbiome and cognitive impairment in patients undergoing peritoneal dialysis.BMC nephrology · 2023Article
- The Dose-Response Effect of Fluoride Exposure on the Gut Microbiome and Its Functional Pathways in Rats.Metabolites · 2023Article
- Causal relationship between gut microbiota and kidney diseases: a two-sample Mendelian randomization study.Frontiers in immunology · 2023Article
- Gut Microbiota Alterations and Primary Glomerulonephritis in Children: A Review.International journal of molecular sciences · 2022Review
- Association of gut microbiota with idiopathic membranous nephropathy.BMC nephrology · 2022Article
- Gut Microbiota in Systemic Lupus Erythematosus and Correlation With Diet and Clinical Manifestations.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing evidences have reported gut microbiota dysbiosis in many diseases, including chronic kidney disease and pediatric idiopathic nephrotic syndrome (INS). There is lack evidence of intestinal microbiota dysbiosis in adults with INS, however. Here, we to address the association between the gut microbiome and INS.
methodsStool samples of 35 adult INS patients and 35 healthy volunteers were collected. Total bacterial DNA was extracted, and the V4 regions of the bacterial 16S ribosomal RNA gene were sequenced. The fecal microbiome was analyzed using bioinformatics. The correlation analysis between altered taxa and clinical parameters was also included.
resultsWe found that microbial diversity in the gut was reduced in adult patients with INS.
conclusionOur findings show compositional alterations of intestinal microbiota in adult patients with INS and correlations between significantly altered taxa and clinical parameters, which points out the direction for the development of new diagnostics and therapeutic approaches targeted intestinal microbiota.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.