Evidence map›Paper›PMID 33681346›Full record

ArticleERJ open research2021

Evaluation of a multicomponent grading system for obstructive sleep apnoea: the Baveno classification.

Winfried J Randerath, Simon Herkenrath, Marcel Treml, Ludger Grote, Jan Hedner, Maria Rosaria Bonsignore, Jean Louis Pépin, Silke Ryan, Sophia Schiza, Johan Verbraecken and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07594288 (Retrospective Evaluation of the Baveno Classification in Comparison With Polysomnography Results in Patients With Obstructive Sleep Apnea), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07594288 completednot on this map

Retrospective Evaluation of the Baveno Classification in Comparison With Polysomnography Results in Patients With Obstructive Sleep Apnea

TypeobservationalSponsorHisar Intercontinental HospitalRan2016 to 2024Enrolled395ConditionsObstructive Sleep Apnea
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 63 citations in OpenAlex.

  1. The role of the Baveno classification system in patients with obstructive sleep apnoea.Lung India : official organ of Indian Chest Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Overall Mortality and Comorbidities in Obstructive Sleep Apnea in Poland.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  6. Review
  7. Article
  8. Central sleep apnea: realignment required.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  9. Article
  10. Article
  11. Symptom content analysis of OSA questionnaires: time to identify and improve relevance of diversity of OSA symptoms?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Observational
  16. The role of oral appliance therapy in obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 8 countries.

Winfried J RanderathInstitute of Pneumology at the University of Cologne, Bethanien Hospital, Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Solingen, Germany.ORCID https://orcid.org/0000-0002-5010-8461
Simon HerkenrathInstitute of Pneumology at the University of Cologne, Bethanien Hospital, Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Solingen, Germany.
Marcel TremlInstitute of Pneumology at the University of Cologne, Bethanien Hospital, Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Solingen, Germany.
Ludger GroteDept of Sleep Medicine, Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-7405-1682
Jan HednerDept of Sleep Medicine, Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Maria Rosaria BonsignorePROMISE Dept, University of Palermo and CNR Institute of Biomedical Research and Innovation (IRIB), Palermo, Italy.ORCID https://orcid.org/0000-0002-4875-7796
Jean Louis PépinHP2 Laboratory, INSERM U1042, Grenoble Alpes University and EFCR Laboratory, Thorax and Vessels Division, Grenoble Alpes University Hospital, Grenoble, France.
Silke RyanDept of Respiratory and Sleep Medicine, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0003-0963-255X
Sophia SchizaDept of Respiratory Medicine, Sleep Disorders Center, Medical School, University of Crete, Heraklion, Greece.
Johan VerbraeckenMultidisciplinary Sleep Disorders Centre, Antwerp University Hospital and University of Antwerp, Edegem-Antwerp, Belgium.
Walter T McNicholasDept of Respiratory and Sleep Medicine, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0001-5927-2738
Athanasia PatakaRespiratory Failure Unit, G. Papanikolaou Hospital, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-3252-6694
Pawel SliwinskiInstitute of Tuberculosis and Lung Diseases, 4th Dept of Respiratory Medicine, Warsaw, Poland.
Özen K BasogluDept of Chest Diseases, Ege University School of Medicine, Izmir, Turkey.ORCID https://orcid.org/0000-0001-8168-6611
University of Cologne · DESahlgrenska University Hospital · SEUniversity College Dublin · IEEge University · TRG. Papanikolaou General Hospital · GRInserm · FRInstitute for Biomedical Research and Innovation · ITUniversity of Antwerp · BEUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New findings on pathophysiology, epidemiology, and outcome have raised concerns on the relevance of the apnoea-hypopnoea index (AHI) in the classification of obstructive sleep apnoea (OSA) severity. Recently, a multicomponent grading system decision integrating symptomatology and comorbidities (Baveno classification), was proposed to characterise OSA and to guide therapeutic decisions. We evaluated whether this system reflects the OSA population, whether it translates into differences in outcomes, and whether the addition of AHI improves the scheme. A total of 14 499 OSA patients from the European Sleep Apnoea Database cohort were analysed. The groups were homogeneously distributed and were found to clearly stratify the population with respect to baseline parameters. Differences in sleepiness and blood pressure between the groups were analysed in a subgroup of patients after 24-36 months of treatment. Group A (minor symptoms and comorbidities) did not demonstrate any effect of treatment on outcome. However, groups B (severe symptoms, minor comorbidities), C (minor symptoms, severe comorbidities) and D (severe symptoms and comorbidities) were associated with improvement in either or both parameters with treatment. The AHI is an essential prerequisite of the diagnosis; however, adding the AHI did not improve the classification. Rather, it was inferior with respect to guiding the treatment decision. Thus, the Baveno classification allows a better stratification of the OSA population and may provide a better guidance for therapeutic decisions in OSA.

Identifiers

PMID33681346
PMCPMC7917384
OpenAlexW3128989116

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.