ReviewERJ open research2021
The safety of cardioselective β
Review in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- An updated insight into the effect of β-adrenergic receptor antagonists (β-blockers) on respiratory function in asthma patients: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Clinical Practice Guideline: Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Guideline
- Guiding student use of generative AI in undergraduate pharmacology: a narrative review and proposed source-checking process framework.Frontiers in medicine · 2026Review
- The association between asthma and heart failure - a systematic review and meta-analysis.European clinical respiratory journal · 2026Review
- Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats.Molecular medicine reports · 2026Article
- Combination Therapy With Beta-Blockers and Angiotensin-Converting Enzyme Inhibitors for Cardiovascular Diseases: Focus on Bisoprolol/Ramipril.Cardiovascular therapeutics · 2026Review
- The beta1-adrenergic receptor in the heart.Cell death discovery · 2025Review
- Bind: large-scale biological interaction network discovery through knowledge graph-driven machine learning.Journal of translational medicine · 2025Article
- Therapeutic competitions and frailty among older adults in São Paulo city: a cross-sectional population-based study, 2015.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Supraventricular tachycardia diagnosis in asthma patients is associated with adverse health outcomes.Pediatric pulmonology · 2024Article
- Review
- Considering Adverse Effects of Common Antihypertensive Medications in the ED.Current hypertension reports · 2024Review
- Intravenous Landiolol for Rate Control in Supraventricular Tachyarrhythmias in Patients with Left Ventricular Dysfunction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Treatable traits in asthma during pregnancy: a call for a shift towards a precision-based management approach.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Allosteric modulator potentiates β2AR agonist-promoted bronchoprotection in asthma models.The Journal of clinical investigation · 2023Article
- Cardioselective versus Non-Cardioselective Beta-Blockers and Outcomes in Patients with Atrial Fibrillation and Chronic Obstructive Pulmonary Disease.Journal of clinical medicine · 2023Article
- Cardiovascular diseases or type 2 diabetes mellitus and chronic airway diseases: mutual pharmacological interferences.Therapeutic advances in chronic disease · 2023Review
- To β-Block or Not to β-Block: That Is Still the Question in Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2022Article
- Identification and Characterization of Preventable Adverse Drug Events in Family Medicine Clinics from Central Saudi Arabia.Saudi journal of medicine & medical sciencesArticle
- Chest Pain at Rest With Unremarkable ECG and Cardiac Enzymes: Case Study Emphasising the Importance of Clinical Suspicion in the Diagnosis of Coronary Artery Disease.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBeta-blockers are key in the management of cardiovascular diseases but blocking airway β
methodsWe searched "asthma" AND "beta-blocker" in PubMed and EmbaseOvid from start to May 2020. The World Health Organization (WHO) global database of individual case safety reports (VigiBase) was searched for reports of fatal asthma or bronchospasm and listed cardioselective β
resultsPubMed and EmbaseOvid searches identified 304 and 327 publications, respectively. No published reports of severe or fatal asthma associated with cardioselective β
conclusionsThere were no published reports of cardioselective β
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.