Evidence map›Paper›PMID 33681257›Full record

ArticleFrontiers in medicine2021

An Open Label Trial to Assess Safety of Losartan for Treating Worsening Respiratory Illness in COVID-19.

Charles D Bengtson, Robert N Montgomery, Usman Nazir, Lewis Satterwhite, Michael D Kim, Nathan C Bahr, Mario Castro, Nathalie Baumlin, Matthias Salathe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Current drug discovery technologies · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Repurposing of Chemotherapeutics to Combat COVID-19.Current topics in medicinal chemistry · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. Present and future treatment strategies for coronavirus disease 2019.Future journal of pharmaceutical sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Charles D BengtsonDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Robert N MontgomeryDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Usman NazirDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Lewis SatterwhiteDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Michael D KimDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Nathan C BahrDepartment of Internal Medicine, Division of Infectious Diseases, University of Kansas Medical Center, Kansas City, KS, United States.
Mario CastroDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Nathalie BaumlinDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Matthias SalatheDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
University of Kansas Medical Center · US

Funding

RADx-UP: Improving the Response of Local Urban and Rural Communities to Disparities in Covid-19 TestingUL1TR002366 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mario Castro, JAMES STEVEN LEEDER · 2017 to 2026
$44.3M
Anti-inflammatory therapy to augment CFTR rescue in CF patientsR01HL133240 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SALATHE, MATTHIAS A · 2017 to 2020
$2.7M
NCATS NIH HHS UL1 TR002366NHLBI NIH HHS R01 HL133240
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

angiotensin receptor inhibitorsBayesianCOVID−19inflammationlosartanrespiratory failure

Identifiers

PMID33681257
PMCPMC7926174
OpenAlexW3129370921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.