Evidence map›Paper›PMID 33681234›Full record

ArticleFrontiers in medicine2020

Self-Balance of Intestinal Flora in Spouses of Patients With Rheumatoid Arthritis.

Zhihui Liu, Yuxi Wu, Yubin Luo, Shixiong Wei, Chenyang Lu, Yi Zhou, Jing Wang, Ting Miao, Hui Lin, Yi Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  7. Nutrients · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Zhihui LiuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yuxi WuDepartment of Rheumatology and Immunology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yubin LuoDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Shixiong WeiDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Chenyang LuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yi ZhouDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Jing WangDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Ting MiaoDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Hui LinDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yi ZhaoDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Qi LiuDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Yi LiuDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CNAffiliated Hospital of Southwest Medical University · CNJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to characterize and assess differences in compositions of intestinal flora between patients with rheumatoid arthritis (RA) and their respective spouses. Eighty volunteers were recruited, including 30 pairs of RA patients and their spouses, and 20 healthy individuals. Fresh stool samples were collected, processed, and 16S rRNA-sequencing was performed. Data were analyzed using an operational taxonomic units-based method, and community structure assessments were performed. Community composition analysis indicated that there were similar intestinal microbiota structures in RA and in their respective spouses. Gut microbiota in spouses of RA were different from those of the healthy controls group, but these differences were not significant. We found that

Indexed as

16S rRNA sequencingenvironment/gene interactiongut microbiotarheumatoid arthritisspouses

Identifiers

PMID33681234
PMCPMC7931358
OpenAlexW3082808010

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.