ArticleFrontiers in bioengineering and biotechnology2021
Activation of Human Osteoblasts via Different Bovine Bone Substitute Materials With and Without Injectable Platelet Rich Fibrin
Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Efficacy of injectable platelet-rich fibrin associated with particulated deproteinized bovine bone mineral in horizontal maxillary regeneration - a randomized, triple blinded, split-mouth controlled clinical trial.Clinical oral investigations · 2026Trial
- Does Injectable Platelet-Rich Fibrin Combined With Autogenous Demineralized Dentine Enhance Alveolar Ridge Preservation? A Randomized Controlled Trial.Clinical oral implants research · 2025Trial
- Biofunctionalization of silk fibroin scaffolds with enamel matrix protein and injectable platelet rich fibrin for soft tissue augmentation: an in-ovo study.International journal of implant dentistry · 2025Article
- A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study.Journal of applied oral science : revista FOB · 2025Article
- A comparative analysis of particulate bovine bone substitutes for oral regeneration: a narrative review.International journal of implant dentistry · 2024Review
- Platelet-rich fibrin for rehydration and pre-vascularization of an acellular, collagen membrane of porcine origin.Clinical oral investigations · 2024Article
- Platelet-rich fibrin as an autologous biomaterial for bone regeneration: mechanisms, applications, optimization.Frontiers in bioengineering and biotechnology · 2024Review
- The Effects of Platelet-Rich Fibrin in the Behavior of Mineralizing Cells Related to Bone Tissue Regeneration-A Scoping Review of In Vitro Evidence.Journal of functional biomaterials · 2023Article
- Alveolar Bone Preservation Using a Combination of Nanocrystalline Hydroxyapatite and Injectable Platelet-Rich Fibrin: A Study in Rats.Current issues in molecular biology · 2023Article
- The application of injectable platelet-rich fibrin in regenerative dentistry: A systematic scoping review ofThe Japanese dental science review · 2022Article
- Hyaluronic Acid with Bone Substitutes Enhance Angiogenesis In Vivo.Materials (Basel, Switzerland) · 2022Article
- Non-Interventional Prospective Observational Study of Platelet Rich Fibrin as a Therapy Adjunctive in Patients with Medication-Related Osteonecrosis of the Jaw.Journal of clinical medicine · 2022Article
- Biomaterials for Periodontal and Peri-Implant Regeneration.Materials (Basel, Switzerland) · 2021Review
- The Influence of Hyaluronic Acid Biofunctionalization of a Bovine Bone Substitute on Osteoblast Activity In Vitro.Materials (Basel, Switzerland) · 2021Article
- Personalized Orbital Fracture Repair: Enhancing 3D-Printed Titanium Mesh with Biomimetic 3D-Printed HAP-COL Frameworks.Romanian journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of the MATERIALS AND
methodsCerabone
resultsFor non-i-PRF groups, the highest values concerning viability were seen for CB at all time points. Pre-treatment with i-PRF increased viability in all groups with the highest values for CB-i-PRF after 3 and 7 and for CX-i-PRF after 10 days. For metabolic activity, the highest rate among non-i-PRF groups was seen for MO at day 3 and for CB at day 7 and 10. Here, i-PRF groups showed higher values than non-i-PRF groups (highest values: CB + i-PRF) at all time points. There was no difference in ALP-expression between groups. For OCN expression in non-i-PRF groups, CB showed the highest values after day 3, CX after day 7 and 10. Among i-PRF-groups, the highest values were seen for CX + i-PRF. At day 3, the highest BMP-2 expression was observed for CX. Here, for i-PRF groups, the highest increase was seen for CX + i-PRF at day 3. At day 7 and 10, there was no significant difference among groups.
conclusionXBSM sintered under high temperature showed increased HOB viability and metabolic activity through the whole period when compared to XBSM manufactured at lower temperatures. Overall, the combination of XBSM with i-PRF improved all cellular parameters, ALP and BMP-2 expression at earlier stages as well as OCN expression at later stages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.