Evidence map›Paper›PMID 33681149›Full record

ReviewFrontiers in chemistry2021

Design of Cyclodextrin-Based Functional Systems for Biomedical Applications.

Wanjia Xu, Xiumei Li, Liang Wang, Siyuan Li, Shengnan Chu, Jiachun Wang, Yijia Li, Jinxing Hou, Quan Luo, Junqiu Liu

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Synthesis of Magnetic Luminescent Nanoparticle FeIndian journal of microbiology · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Biomimetic Construction of Artificial Selenoenzymes.Biomimetics (Basel, Switzerland) · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wanjia XuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Xiumei LiState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Liang WangState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Siyuan LiState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Shengnan ChuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Jiachun WangKey Laboratory of Emergency and Trauma, Ministry of Education, College of Emergency and Trauma, Hainan Medical University, Haikou, China.
Yijia LiState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Jinxing HouState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Quan LuoState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.
Junqiu LiuState Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclodextrins (CDs) are a family of α-1,4-linked cyclic oligosaccharides that possess a hydrophobic cavity and a hydrophilic outer surface with abundant hydroxyl groups. This unique structural characteristic allows CDs to form inclusion complexes with various guest molecules and to functionalize with different substituents for the construction of novel sophisticated systems, ranging from derivatives to polymers, metal-organic frameworks, hydrogels, and other supramolecular assemblies. The excellent biocompatibility, selective recognition ability, and unique bioactive properties also make these CD-based functional systems especially attractive for biomedical applications. In this review, we highlight the characteristics and advantages of CDs as a starting point to design different functional materials and summarize the recent advances in the use of these materials for bioseparation, enzymatic catalysis, biochemical sensing, biomedical diagnosis and therapy.

Indexed as

biomedical applicationscyclodextrinfunctional materialsinclusion complexesselective recognition

Identifiers

PMID33681149
PMCPMC7931691

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.