Evidence map›Paper›PMID 33680907›Full record

ArticleFrontiers in oncology2020

CT-Guided Pelvic Lymph Nodal Brachytherapy.

Hiroaki Kunogi, I-Chow Hsu, Nanae Yamaguchi, Soshi Kusunoki, Keiko Nakagawa, Yayoi Sugimori, Kazunari Fujino, Yasuhisa Terao, Daiki Ogishima, Ryoichi Yoshimura and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Hiroaki KunogiDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
I-Chow HsuDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, United States.
Nanae YamaguchiDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Soshi KusunokiDepartment of Gynecology, Juntendo University, Tokyo, Japan.
Keiko NakagawaDepartment of Radiation Oncology, Tokyo Medical Dental University, Tokyo, Japan.
Yayoi SugimoriDepartment of Gynecology, Juntendo University, Tokyo, Japan.
Kazunari FujinoDepartment of Gynecology, Juntendo University, Tokyo, Japan.
Yasuhisa TeraoDepartment of Gynecology, Juntendo University, Tokyo, Japan.
Daiki OgishimaDepartment of Gynecology, Juntendo University, Tokyo, Japan.
Ryoichi YoshimuraDepartment of Radiation Oncology, Tokyo Medical Dental University, Tokyo, Japan.
Keisuke SasaiDepartment of Radiation Oncology, Juntendo University, Tokyo, Japan.
Juntendo University · JPTokyo Medical and Dental University · JPUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis is a report of our initial experience using computed tomography (CT)-guided interstitial high dose rate (HDR) brachytherapy to treat bulky pelvic nodal metastases as a part of definitive radiotherapy. MATERIAL AND

methodsBetween February 2015 and April 2019, 14 cervical/endometrial cancer patients presenting with bulky pelvic node(s) underwent nodal interstitial brachytherapy boost in our institution. In total, 17 nodes were treated. The median maximum diameters of the positive nodes at the time of diagnosis and at the first nodal implant were 25 mm (range: 10-65 mm) and 16 mm (range: 9-51 mm), respectively. Dosimetry data of the lymph nodal target volume and small bowel were collected and compared using the paired-sample

resultsThe median follow-up time for all patients was 26 months. Local recurrence in pelvic nodes occurred in one patient (7%) after 16 months. One patient experienced grade 3 bladder bleeding, and one patient experienced grade 2 pubic bone fracture. No patient had grade 2 or greater gastrointestinal toxicity. In the dosimetric analysis, the mean nodal brachytherapy D

conclusionsCT-guided interstitial HDR pelvic nodal brachytherapy appears to be well tolerated with excellent local control in cervical or endometrial cancer patients with bulky pelvic nodes. This approach may offer a useful therapeutic option for unresected bulky pelvic nodes.

Indexed as

CT guidancegynecological malignanciesinterstitial brachytherapynodal brachytherapypelvic lymph node

Identifiers

PMID33680907
PMCPMC7933543
OpenAlexW3133140654

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.