Evidence map›Paper›PMID 33680893›Full record

ArticleRestorative dentistry & endodontics2021

Biocompatibility and bioactive potential of the NeoMTA Plus endodontic bioceramic-based sealer.

Roberto Alameda Hoshino, Mateus Machado Delfino, Guilherme Ferreira da Silva, Juliane Maria Guerreiro-Tanomaru, Mário Tanomaru-Filho, Estela Sasso-Cerri, Paulo Sérgio Cerri

Abstract read
In one paragraph

Article in Restorative dentistry & endodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roberto Alameda HoshinoDepartment of Restorative Dentistry, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0002-2123-3001
Mateus Machado DelfinoDepartment of Restorative Dentistry, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0002-6386-9200
Guilherme Ferreira da SilvaPro-Rectory of Research and Post-graduation, School of Dentistry, Universidade Sagrado Coração (USC), Bauru, SP, Brazil.ORCID https://orcid.org/0000-0002-8019-6714
Juliane Maria Guerreiro-TanomaruDepartment of Restorative Dentistry, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0003-0446-2037
Mário Tanomaru-FilhoDepartment of Restorative Dentistry, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0002-2574-4706
Estela Sasso-CerriDepartment of Morphology, Genetics, Orthodontics and Pediatric Dentistry, Laboratory of Histology and Embryology, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0002-9148-3081
Paulo Sérgio CerriDepartment of Morphology, Genetics, Orthodontics and Pediatric Dentistry, Laboratory of Histology and Embryology, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID https://orcid.org/0000-0001-5756-5828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study evaluated the biocompatibility and bioactive potential of NeoMTA Plus mixed as a root canal sealer in comparison with MTA Fillapex. MATERIALS AND

methodsPolyethylene tubes filled with NeoMTA Plus (

resultsAt 7 days, the capsules around NeoMTA Plus and MTA Fillapex had more ICs and IL-6-immunostained cells than the CG. However, at 60 days, there was no significant difference in the IC number between NeoMTA Plus and the CG (

conclusionsThe NeoMTA Plus root canal sealer is biocompatible and exhibits bioactive potential.

Indexed as

Bioactive potentialBiocompatibilityImmunohistochemistryInflammatory reactionInterleukin-6

Identifiers

PMID33680893
PMCPMC7906839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.