Evidence map›Paper›PMID 33680861›Full record

ArticleAsia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology2021

Evaluation of the degenerative pattern of PCL in osteoarthritis patients using UTE-T2 mapping.

Seiju Hayashi, Tomoyuki Nakasa, Yoshiko Matsuoka, Yuji Akiyama, Masakazu Ishikawa, Atsuo Nakamae, Kazuo Awai, Nobuo Adachi

Open access · goldAbstract read
In one paragraph

Article in Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Seiju HayashiDepartment of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Tomoyuki NakasaDepartment of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Yoshiko MatsuokaDepartment of Clinical Radiology, Hiroshima University Hospital Clinical Support, Hiroshima, Japan.
Yuji AkiyamaDepartment of Clinical Radiology, Hiroshima University Hospital Clinical Support, Hiroshima, Japan.
Masakazu IshikawaDepartment of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Atsuo NakamaeDepartment of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Kazuo AwaiDepartment of Diagnostic Radiology, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Nobuo AdachiDepartment of Orthopaedic Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Hiroshima University · JPHiroshima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe posterior cruciate ligament (PCL) is one of the essential stabilizers of the knee joint and it was demonstrated that its degenerative change related to the knee osteoarthritis (OA). We aimed to evaluate signal of the PCL in OA patients in comparison with healthy young and elderly volunteers using the ultra-short echo timeenhanced (UTE)-T2∗ mapping, and to validate these findings with histology.

methodsThirty asymptomatic volunteers, 13 young people (younger group) and 17 elderly people (elder group), and 27 patients who had undergone total knee arthroplasty (OA group) were enrolled in this study. UTE-T2∗ maps of PCL were obtained from all participants. The PCL was divided into proximal, middle, and distal parts and the UTET2∗ values obtained from each part were compared among the groups. In OA group, the sacrificed PCLs were evaluated histologically in each part corresponding to the part of UTE-T2∗ maps and compared.

resultsThe UTE-T2∗ values in OA group were significantly higher than those in other groups except in distal part. In elder group, the UTE-T2∗ values were significantly higher than those in younger group only in the proximal part. Moreover, in OA group, the UTE-T2∗ values in proximal and middle parts were significantly higher than those in distal part. There was a moderate correlation between the UTE-T2∗ values and histological scores.

conclusionsThe specific signal intensity pattern of the PCL in patients with OA was demonstrated using UTE-T2∗ mapping, and these findings were related to histological degenerated status of the PCL.

Indexed as

Magnetic resonance image (MRI)Osteoarthritis (OA)Posterior cruciate ligament (PCL)Ultra-short echo time-enhanced (UTE)

Identifiers

PMID33680861
PMCPMC7899951
OpenAlexW3130279478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.