ArticleIntegrative medicine research2021
Efficacy and safety of fermented oyster extract for height of children with short stature: a randomized placebo-controlled trial.
Article in Integrative medicine research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Effect of Fermented Sarco Oyster (International journal of environmental research and public health · 2022Trial
- Article
- Fermented oyster extract promotes height growth in children with mild short stature: a randomized, double-blind, placebo-controlled trial.Nutrition research and practice · 2026Article
- Fermented Oyster Extract Improves Linear Growth in Children with Idiopathic Short Stature: A Randomized, Double-Blind, Placebo-Controlled Trial.Preventive nutrition and food science · 2026Article
- Comparative effectiveness of East Asian traditional medicine for treatment of idiopathic short stature in children: Systematic review and network meta-analysis.Integrative medicine research · 2022Review
- Effect of fermented oyster (Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome experimental studies have established the effect of oysters on the promotion of body growth. Yet, there is a lack of human clinical studies. The objective of this study was to evaluate the effect of a fermented oyster (FO) extract on the increase in the height of children with stature in the 25th percentile by age.
methodsIn total, 100 children (6-11 years old) were randomly divided into two (FO or control) groups. For 24 weeks, the subjects in the FO group took the FO extract once daily before sleeping, whereas the control group took placebo extracts, simultaneously. We evaluated the height gain, height velocity (HV), height standard deviation score (SDS), urine deoxypyridinoline (DPD), growth hormone (GH), insulin-like growth factor (IGF-1), and IGF binding protein 3 (IGFBP-3).
resultsThe height gain and height SDS were significantly higher in the FO group than in the placebo group after 24 weeks (height gain:
conclusionFO supplementation may help to increase the height of children, and the effect might be mediated via effects on the IGFBP-3 levels.
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