ArticleAfrican journal of emergency medicine : Revue africaine de la medecine d'urgence2021
Prevalence and outcome of sepsis and septic shock in intensive care units in Addis Ababa, Ethiopia: A prospective observational study.
Article in African journal of emergency medicine : Revue africaine de la medecine d'urgence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07079605 (Cardiac Manifestations of Sepsis and Its Association With Disease Outcome), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiac Manifestations of Sepsis and Its Association With Disease Outcome: A Prospective Cohort Study
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and Risk Factors Associated With ICU Mortality in Ethiopia: A Systemic Review and Meta-Analysis.Nursing open · 2025Pooled it
- Isolated pathogens, antimicrobial susceptibility, and clinical outcomes in intensive care unit patients at a tertiary hospital in Ethiopia: a retrospective cross sectional study.BMC anesthesiology · 2026Article
- Predictors of ICU mortality in septic patients in a resource-limited African setting: a prospective multicenter cohort study in Lubumbashi, DRC.Journal of anesthesia, analgesia and critical care · 2026Article
- Patterns and predictors of readmission among sepsis survivors in a tertiary emergency department in Ethiopia.IJID regions · 2026Article
- Article
- Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia.BMC infectious diseases · 2025Article
- Bacteriological profile and antimicrobial resistance in sepsis cases in intensive care units in Lubumbashi: challenges and perspectives.Annals of clinical microbiology and antimicrobials · 2025Article
- Characteristics and In-Hospital Outcomes of Patients With Septic Shock in the Adult Medical Intensive Care Unit of a Tertiary Hospital in Ethiopia: A Prospective Observational Study.Health science reports · 2025Article
- Observational
- Prevalence & risk factors of multi-morbidity in critically ill patients with sepsis-associated acute kidney injury (SA-AKI).The Indian journal of medical research · 2025Article
- Epidemiology, Ventilation Management, and Outcomes in Invasively Ventilated Coronavirus Disease 2019 Patients: An Analysis of Four Observational Studies in Four Countries on Two Continents.The American journal of tropical medicine and hygiene · 2025Observational
- A systematic review of the avian antibody (IgY) therapeutic effects on human bacterial infections over the decade.Antibody therapeutics · 2025Review
- Article
- Sepsis among Adults Admitted to Intensive Care Unit of a Tertiary Care Centre.JNMA; journal of the Nepal Medical Association · 2024Article
- Mortality due to Sepsis and Its Associated Factors Among Patients Admitted to Intensive Care Units of Southern Amhara Public Hospitals, Ethiopia.BioMed research international · 2024Article
- Sepsis among Patients Admitted to the Intensive Care Unit of a Tertiary Care Centre.JNMA; journal of the Nepal Medical Association · 2023Article
- The magnitude of mortality and its determinants in Ethiopian adult intensive care units: A systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2022Review
- Knowledge and Associated Factors Towards Sepsis Management Among Nurses Working in the Emergency Department of Public Hospitals in Addis Ababa.SAGE open nursingArticle
- Magnitude of Septic Shock and its Associated Factors Among Critically Ill COVID-19 Patients at Addis Ababa COVID-19 Care Centers, Ethiopia.SAGE open nursingArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis and septic shock are the major causes of morbidity and mortality in Intensive care Units (ICUs) in low and middle-income countries. However, little is known about their prevalence and outcome in these settings. The study aimed to assess the prevalence and outcome of sepsis and septic shock in ICUs in Addis Ababa, Ethiopia.
methodsA prospective observational study was conducted from March 2017 to February 2018 in four selected ICUs in Addis Ababa from a total of twelve hospitals having ICU services. There were 1145 total ICU admissions during the study period. All admissions into those ICUs with sepsis, severe sepsis, and septic shock using the Systemic Inflammatory Response Syndrome (SIRS) criteria (SEPSIS-2) during the study period were screened for sepsis or septic shock based on the new sepsis definition (SEPSIS-3). All patients with sepsis and septic shock during ICU admission were included and followed for 28 days of ICU admission. Data analysis was done using the Statistical Package for Social Sciences (SPSS) software version 20.0.
resultsA total of 275 patients were diagnosed with sepsis and septic shock. The overall prevalence of sepsis and septic shock was 26.5 per 100 ICU admissions. The most frequent source of sepsis was respiratory infection (53.1%). The median length of stay in the ICUs was 5 (IQR, 2-8) days. The most common bacterium isolate was
conclusionSepsis and septic shock are common among our ICU admissions, and are associated with a high mortality rate.
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