ArticleAfrican journal of emergency medicine : Revue africaine de la medecine d'urgence2021
A retrospective comparison of the burden of organophosphate poisoning to an Intensive Care Unit in Soweto over two separate periods.
Article in African journal of emergency medicine : Revue africaine de la medecine d'urgence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Reporting of notifiable medical conditions among emergency department doctors in Gauteng.Southern African journal of infectious diseases · 2026Article
- Acute organophosphorus toxicity in a regional hospital in Johannesburg, South Africa: A retrospective chart review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2023Article
- Pattern and outcome of acute organophosphate poisoning at health facilities of Harari Region, Eastern Ethiopia.SAGE open medicine · 2023Article
- Organophosphate Poisoning in a Paediatric Intensive Care Unit: A Retrospective Analysis Based on Ten Years of Experience.International journal of general medicine · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOrganophosphate poisoning (OPP) is a major health-care burden in South Africa. Recently, we have observed that patients admitted to our Intensive Care Unit (ICU) with OPP have followed a more complicated course in comparison to previous years.
objectivesTo describe the differences in the clinical course and costs of patients with OPP between two time periods, namely 2012 and 2017.
methodsRetrospective comparison of patients admitted to the Intensive Care Unit (ICU) of Chris Hani Baragwanath Academic Hospital between January 2012 to December 2012 and January 2017 to December 2017.
resultsForty-one patients were found in the database. Patients from our 2017 cohort showed a significantly longer total median (IQR) length of stay 8 (4-17) days vs. 2 (2-3) days, p = 0.000, duration of antidote therapy 5 (3-10) days vs. 2 (2-3) days, p = 0.004 and duration of ventilation 4 (2-11) days vs 1 (1-2) day, p = 0.003. Patients presenting in 2017 were more likely to be admitted to ICU, odds ratio 5.6 (CI 1.2-26). There was a 31- fold increase in ICU costs between 2012 and 2017.
conclusionBased on our experience, the clinical course of OPP requiring ICU admission has evolved into a condition with a longer length of stay, duration of antidote therapy, ventilatory support, increased risk of complications and additional costs.
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