ArticleBiomedical optics express2021
Comparative study of autofluorescence in flat and tapered optical fibers towards application in depth-resolved fluorescence lifetime photometry in brain tissue.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Article
- Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution.bioRxiv : the preprint server for biology · 2025Article
- Emerging technologies toward the integration of multiple functionalities on non-planar implantable neurophotonics probes.Neurophotonics · 2024Article
- 110 μm thin endo-microscope for deep-brain in vivo observations of neuronal connectivity, activity and blood flow dynamics.Nature communications · 2023Article
- Orthogonalization of far-field detection in tapered optical fibers for depth-selective fiber photometry in brain tissue.APL photonics · 2022Article
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
- Influence of the anatomical features of different brain regions on the spatial localization of fiber photometry signals.Biomedical optics express · 2021Article
- Automated microscope-independent fluorescence-guided micropipette.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
As the scientific community seeks efficient optical neural interfaces with sub-cortical structures of the mouse brain, a wide set of technologies and methods is being developed to monitor cellular events through fluorescence signals generated by genetically encoded molecules. Among these technologies, tapered optical fibers (TFs) take advantage of the modal properties of narrowing waveguides to enable both depth-resolved and wide-volume light collection from scattering tissue, with minimized invasiveness with respect to standard flat fiber stubs (FFs). However, light guided in patch cords as well as in FFs and TFs can result in autofluorescence (AF) signal, which can act as a source of time-variable noise and limit their application to probe fluorescence lifetime
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Registered trials
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