Evidence map›Paper›PMID 33680505›Full record

ArticleApplied sciences (Basel, Switzerland)2021

Deep Learning-Based Methods for Prostate Segmentation in Magnetic Resonance Imaging.

Albert Comelli, Navdeep Dahiya, Alessandro Stefano, Federica Vernuccio, Marzia Portoghese, Giuseppe Cutaia, Alberto Bruno, Giuseppe Salvaggio, Anthony Yezzi

Abstract read
In one paragraph

Article in Applied sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Albert ComelliRi.MED Foundation, Via Bandiera, 11, 90133 Palermo, Italy.ORCID 0000-0002-9290-6103
Navdeep DahiyaDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0002-6275-6845
Alessandro StefanoInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015 Cefalù, Italy.ORCID 0000-0002-7189-1731
Federica VernuccioDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND), University of Palermo, 90127 Palermo, Italy.
Marzia PortogheseDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND), University of Palermo, 90127 Palermo, Italy.
Giuseppe CutaiaDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND), University of Palermo, 90127 Palermo, Italy.
Alberto BrunoDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND), University of Palermo, 90127 Palermo, Italy.
Giuseppe SalvaggioDipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-2465-1185
Anthony YezziDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Funding

Quantification of myocardial blood flow using Dynamic PET/CTA fused imagery to determine physiological significance of specific coronary lesionsR01HL143350 · NHLBI · EMORY UNIVERSITY · PI PICCINELLI, MARINA · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL143350
6 · The paper itself

Abstract

Magnetic Resonance Imaging-based prostate segmentation is an essential task for adaptive radiotherapy and for radiomics studies whose purpose is to identify associations between imaging features and patient outcomes. Because manual delineation is a time-consuming task, we present three deep-learning (DL) approaches, namely UNet, efficient neural network (ENet), and efficient residual factorized convNet (ERFNet), whose aim is to tackle the fully-automated, real-time, and 3D delineation process of the prostate gland on T2-weighted MRI. While UNet is used in many biomedical image delineation applications, ENet and ERFNet are mainly applied in self-driving cars to compensate for limited hardware availability while still achieving accurate segmentation. We apply these models to a limited set of 85 manual prostate segmentations using the k-fold validation strategy and the Tversky loss function and we compare their results. We find that ENet and UNet are more accurate than ERFNet, with ENet much faster than UNet. Specifically, ENet obtains a dice similarity coefficient of 90.89% and a segmentation time of about 6 s using central processing unit (CPU) hardware to simulate real clinical conditions where graphics processing unit (GPU) is not always available. In conclusion, ENet could be efficiently applied for prostate delineation even in small image training datasets with potential benefit for patient management personalization.

Indexed as

deep learningENetERFNetMRIprostateradiomicssegmentationUNet

Identifiers

PMID33680505
PMCPMC7932306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.