Evidence map›Paper›PMID 33680492›Full record

ArticleObesity science & practice2021

Predictors of liver fat among children and adolescents from five different ethnic groups.

Gertraud Maskarinec, Andrea K Garber, Michael C Wong, Nisa Kelly, Leila Kazemi, Steven D Buchthal, Nicole Fearnbach, Steven B Heymsfield, John A Shepherd

Abstract read
In one paragraph

Article in Obesity science & practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gertraud MaskarinecUniversity of Hawaii Cancer Center Honolulu Hawaii USA.ORCID https://orcid.org/0000-0002-8129-958X
Andrea K GarberUniversity of California at San Francisco San Francisco California USA.
Michael C WongUniversity of Hawaii Cancer Center Honolulu Hawaii USA.ORCID https://orcid.org/0000-0003-2392-9253
Nisa KellyUniversity of Hawaii Cancer Center Honolulu Hawaii USA.
Leila KazemiUniversity of Hawaii Cancer Center Honolulu Hawaii USA.
Steven D BuchthalUniversity of Hawaii Cancer Center Honolulu Hawaii USA.
Nicole FearnbachPennington Biomedical Research Center Baton Rouge Louisiana USA.ORCID https://orcid.org/0000-0001-9208-830X
Steven B HeymsfieldPennington Biomedical Research Center Baton Rouge Louisiana USA.ORCID https://orcid.org/0000-0003-1127-9425
John A ShepherdUniversity of Hawaii Cancer Center Honolulu Hawaii USA.

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
ZIDOVUDINE &LAMIVUDINE &NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFM01RR001271 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$22.7M
Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUMMEL, MATTHEW F · 2003 to 2019
$21.8M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Multi-center Randomized Controlled Trial of Refeeding in Anorexia NervosaR01HD082166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARBER, ANDREA K · 2015 to 2025
$5.7M
Shape up! KidsR01DK111698 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI HEYMSFIELD, STEVEN, SHEPHERD, JOHN ALAN · 2017 to 2021
$3.3M
NCRR NIH HHS M01 RR001271NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK072476NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK111698
6 · The paper itself

Abstract

objectivesAs rates of obesity around the world have increased, so has the detection of high level of liver fat in children and adolescents. This may put them at risk for cardiovascular disease later in life. This analysis of a cross-sectional population-based study of children and adolescents evaluated demographic and lifestyle determinants of percent liver fat.

methodsHealthy participants (123 girls and 99 boys aged 5-17 years) recruited by convenience sampling in three locations completed questionnaires, anthropometric measurements, and dual X-ray absorptiometry and magnetic resonance imaging (MRI) assessment. General linear models were applied to estimate the association of demographic, anthropometric, and dietary factors as well as physical activity with MRI-based percent liver fat.

resultsThe strongest predictor of liver fat was body mass index (BMI;

conclusionsThis study in multiethnic children and adolescents confirms the strong relationship of BMI with percent liver fat even in a population with low liver fat levels without detecting an association with age, sex, and dietary or physical activity patterns.

Indexed as

childrendietethnicityliver fatMRIobesity

Identifiers

PMID33680492
PMCPMC7909587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.