Evidence map›Paper›PMID 33680455›Full record

ArticleMolecular and clinical oncology2021

Electrochemotherapy in Kaposi sarcoma: A systematic review.

Martina Ferioli, Andrea Galuppi, Milly Buwenge, Silvia Cammelli, Anna Myriam Perrone, Gabriella Macchia, Francesco Deodato, Savino Cilla, Alice Zamagni, Francesca De Terlizzi and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. The Diagnosis and Management of Cutaneous Metastases from Melanoma.International journal of molecular sciences · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Martina FerioliRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
Andrea GaluppiRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
Milly BuwengeRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
Silvia CammelliRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
Anna Myriam PerroneOncologic Gynaecology Unit, Department Medical and Surgical Sciences (DIMEC), University of Bologna, S. Orsola-Malpighi Hospital, I-40138 Bologna, Italy.
Gabriella MacchiaRadiotherapy Unit, Gemelli Molise Hospital, Fondazione Policlinico Universitario A. Gemelli, IRCCS, I-86100 Campobasso, Italy.
Francesco DeodatoRadiotherapy Unit, Gemelli Molise Hospital, Fondazione Policlinico Universitario A. Gemelli, IRCCS, I-86100 Campobasso, Italy.
Savino CillaMedicalPhysic Unit, Gemelli Molise Hospital, Fondazione Policlinico Universitario A. Gemelli, IRCCS, I-86100 Campobasso, Italy.
Alice ZamagniRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
Francesca De TerlizziScientific and Medical Department IGEA S.p.A., I-41012 Carpi (Mo), Italy.
Luca TagliaferriFondazione Policlinico Universitario 'A. Gemelli' IRCCS, UOC di Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, I-00168 Roma, Italy.
Pierandrea De IacoOncologic Gynaecology Unit, Department Medical and Surgical Sciences (DIMEC), University of Bologna, S. Orsola-Malpighi Hospital, I-40138 Bologna, Italy.
Alessio Giuseppe MorgantiRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, I-40138 Bologna, Italy.
University of Bologna · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITAgostino Gemelli University Polyclinic · ITIGEA Clinical Biophysics (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kaposi sarcoma (KS) is a rare angioproliferative disorder, which is usually associated with human herpesvirus-8 infection. Electrochemotherapy (ECT) may be an option in the treatment of KS skin lesions due to the high response rate noted in neoplastic lesions of different histological types. The aim of the present systematic review was to analyse the available evidence on using ECT in the treatment of KS skin lesions. Tumor response, local control and toxicity were analyzed. In the three included studies, the complete response rate was 65-100% and the overall response rate in all studies was 100%. The treatment was well tolerated with mild and transient toxicity. However, further studies are required to fully analyze long-term disease control and to compare ECT with other local therapies used for KS.

Indexed as

electrochemotherapyhuman herpesvirus-8Kaposi sarcomaskin lesionssystematic review

Identifiers

PMID33680455
PMCPMC7890459
OpenAlexW3128145550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.