ArticlePain research & management2021
Chronic Pain after Open Appendectomy and Its Effects on Quality of Life in Children Aged 8-18 Years.
Article in Pain research & management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07629362 (Chronic Postoperative Pain After Appendectomy), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Postoperative Pain After Appendectomy: A Prospective Observational Study
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Prevalence of and recommendation for measuring chronic postsurgical pain in children: an updated systematic review and meta-analysis.Regional anesthesia and pain medicine · 2025Pooled it
- Ibuprofen for acute postoperative pain in children.The Cochrane database of systematic reviews · 2024Pooled it
- Esketamine combined with hydromorphone versus hydromorphone for post-operative patient-controlled intravenous analgesia in children: a randomized controlled trial.European journal of medical research · 2026Trial
- Cryoanalgesia for Pain Management After Pectus Excavatum Repair (COPPER) in Adolescents: A Randomized Controlled Trial.Paediatric anaesthesia · 2025Trial
- Effect of Ondansetron on Postoperative Pain and Vomiting after Acute Appendicitis Surgery: A Placebo-Controlled Double-Blinded Randomized Clinical Trial.Pain research & management · 2024Trial
- Presurgical Prognostic Factors for Chronic Postsurgical Pain Across Developmental Stages in Children, Adolescents, and Young Adults: A Systematic Review and Meta-Analysis.Journal of pain research · 2026Review
- Chronic postsurgical pain in young children: Prevalence, pain trajectories and physical and psychological prognostic factors.The journal of pain · 2025Observational
- Dorsal Root Ganglion Pulsed Radiofrequency with Scar Radiofrequency Ablation Combined for Chronic Postoperative Abdominal Pain: A Retrospective Study.Journal of pain research · 2025Article
- Efficiency and Impact of Hypnoanalgesia for Cardiac Catheterisation in Paediatric Population.Journal of clinical medicine · 2023Article
- Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies.BMJ medicine · 2022Review
- Mapping the current state of pediatric surgical pain care across Canada and assessing readiness for change.Canadian journal of pain = Revue canadienne de la douleur · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic postsurgical pain is an important problem for both children and adults. This study aims to investigate the prevalence of chronic postappendectomy pain (CPAP) in children and its social and physical effects. Methods: This prospective observational study was conducted on children aged 8-18 years who had undergone open appendectomies. In the sixth month after the surgical procedure, the presence of chronic pain was examined in the lower right abdominal area. CPAP and its effects on children's daily life activities were assessed using the numeric rating scale (NRS) and the Pediatric Quality of Life Scale (PedsQL). Results: Analysis was performed on 158 children, 97 of whom were boys (61.4%) and 61 were girls (38.6%). The average age was 12.8 ± 3 years, the average NRS was 4.48 ± 1.1, and the average scar length was 6.09 ± 1.6 cm. Twenty-nine children described CPAP, and its prevalence at six months after the surgery was 18.4%. Of these, 16 (55.2%) complained of pain only during exercise and 13 (44.8%) experienced pain while resting. The rate of CPAP was significantly higher in girls. Female gender and longer scar length were associated with the development of chronic pain. The PedsQL scores from the children's self-reports and their parents' reports were significantly lower for children who described CPAP as compared to those without CPAP. Conclusion: CPAP occurs quite frequently in children, especially in girls, and negatively affects children's quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.