Evidence map›Paper›PMID 33680216›Full record

ArticleDisease markers2021

Golgi Phosphoprotein 3 Represents a Novel Tumor Marker for Gastric and Colorectal Cancers.

Chun-Xiao Wang, Hai-Bin Zhuang, Ze-Sheng Shi, Cheng-Zhi Qiu, Zhi-Xiong Chen, Long-Feng Tang

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chun-Xiao WangDepartment of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.ORCID https://orcid.org/0000-0001-5914-1447
Hai-Bin ZhuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, China.ORCID https://orcid.org/0000-0002-1500-6881
Ze-Sheng ShiDepartment of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.ORCID https://orcid.org/0000-0002-6725-7017
Cheng-Zhi QiuDepartment of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.ORCID https://orcid.org/0000-0002-5228-9104
Zhi-Xiong ChenDepartment of General Surgery, Xiamen Hospital of T.C.M., Xiamen, Fujian Province, China.
Long-Feng TangDepartment of Orthopedics, ANXI County Hospital, Quanzhou, Fujian Province, China.
Fujian Medical University · CNXiamen Chang Gung Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly diagnosis is very important for the clinical treatment of gastric cancer (GC) and colorectal cancer (CRC). We aimed to detect Golgi phosphoprotein 3 (GOLPH3) and evaluate its diagnostic value. MATERIALS AND

methodsSerum concentrations of GOLPH3 were detected by ELISA in 136 CRC patients, 102 GC patients, and 50 healthy controls at the Second Affiliated Hospital of Fujian Medical University from June 2016 to December 2019. Serum concentrations of CEA and CA19-9 were detected by ECLIA.

resultsSerum concentrations of GOLPH3, CEA, and CA19-9 were higher in GC and CRC patients than in healthy controls (

conclusionSerum GOLPH3 concentrations in GC and CRC patients are related to TNM stage. GOLPH3 may represent a novel biomarker for the diagnosis of GC and CRC. The combination of serum GOLPH3, CEA, and CA19-9 concentrations can improve diagnostic efficiency for GC and CRC. GOLPH3 is expected to become an indicator for the early diagnosis and evaluation of surgical effects.

Indexed as

Antigens, Tumor-Associated, CarbohydrateCarcinoembryonic AntigenColorectal NeoplasmsFemaleHumansMaleMembrane ProteinsMiddle AgedNeoplasm MetastasisStomach NeoplasmsAntigens, Tumor-Associated, Carbohydratecarbohydrate antigen 199, humanCarcinoembryonic AntigenGOLPH3 protein, humanMembrane Proteins

Identifiers

PMID33680216
PMCPMC7929655
OpenAlexW3130177534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.