Evidence map›Paper›PMID 33680107›Full record

ArticleExperimental and therapeutic medicine2021

Schisantherin A improves learning and memory abilities partly through regulating the Nrf2/Keap1/ARE signaling pathway in chronic fatigue mice.

Huijiao Lin, Xinyun Zhang, Jiawei Liu, Liwei Yuan, Jiale Liu, Chunmei Wang, Jinghui Sun, Jianguang Chen, Shu Jing, He Li

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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  8. An analysis of the nutritional effects ofFrontiers in nutrition · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huijiao LinDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Xinyun ZhangDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Jiawei LiuDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Liwei YuanDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Jiale LiuNeurology Department, Jilin City Central Hospital, Jilin, Jilin 132011, P.R. China.
Chunmei WangDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Jinghui SunDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Jianguang ChenDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Shu JingGeneral Surgery Department, Affiliated Hospital of Beihua University, Jilin, Jilin 132011, P.R. China.
He LiDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, Jilin 132013, P.R. China.
Beihua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic fatigue is frequently accompanied by decreased learning and memory capabilities. Schizantherin A (SCA) is one of the main active monomer components in

Indexed as

apoptosisbrainfatiguenuclear factor (erythroid-derived 2)-like 2-kelch-like ECH-associated protein 1-antioxidant response element pathwaySchisantherin A

Identifiers

PMID33680107
PMCPMC7918174
OpenAlexW3132513762

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.