Evidence map›Paper›PMID 33680022›Full record

ArticleIranian journal of pharmaceutical research : IJPR2020

Synthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line.

Marzieh Gerami, Modjtaba Emadi-Baygi, Mohammad Eshghi, Fatemeh Elahian, Razieh Heidari, Mehdi Hosseinzadeh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Marzieh GeramiDepartment of Computer Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Modjtaba Emadi-BaygiDepartment of Genetics, Faculty of Basic Sciences, Shahrekord University, Shahrekord, Iran.
Mohammad EshghiDepartment of Computer Engineering, Faculty of Computer and Electrical Engineering, Shahid Beheshti University, Tehran, Iran.
Fatemeh ElahianDepartment of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Razieh HeidariDepartment of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mehdi HosseinzadehInstitute of Research and Development, Duy Tan University, Da Nang 550000, Vietnam.
Shahrekord University of Medical Sciences · IRIran University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRShahid Beheshti University · IRShahrekord University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological circuits are developed as biological parts within a cell to carry out logical functions resembling those studied in electronics circuits. These circuits can be performed as a method to vary cellular functions, to develop cellular responses to environmental conditions, or to regulate cellular developments. This research explored the possibility of synthetic biology based on the genetic logic circuit

Indexed as

BCRPLentiviral vectorsLogical circuitsMCF-7 Cancer cell lineSynthetic biology

Identifiers

PMID33680022
PMCPMC7757972
OpenAlexW3135489348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.