Evidence map›Paper›PMID 33680003›Full record

ArticleJournal of exercise science and fitness2021

Comparison of whole-body vibration training and quadriceps strength training on physical function and neuromuscular function of individuals with knee osteoarthritis: A randomised clinical trial.

Zhangqi Lai, Seullee Lee, Yiyang Chen, Lin Wang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of exercise science and fitness, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07180485 (The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity), which is not on this map. Cited by 15 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 6 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180485 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity

TypeinterventionalSponsorDalin Tzu Chi General HospitalRan2025 to 2027Enrolled120ConditionsDynapenia, Abdominal ObesityArmswhole body vibration training, control group
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 6 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  4. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Zhangqi LaiSchool of Kinesiology, Shanghai University of Sport, Shanghai, China.
Seullee LeeSchool of Kinesiology, Shanghai University of Sport, Shanghai, China.
Yiyang ChenDepartment of Kinesiology and Physical Education, McGill University, Montreal, Canada.
Lin WangSchool of Kinesiology, Shanghai University of Sport, Shanghai, China.
Shanghai University of Sport · CNMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is one of the leading causes of global disability, which causes knee pain, stiffness and swelling. Impaired neuromuscular function may cause joint instability, alignment changes and knee stress, which leads to the progression of KOA. Whole-body vibration (WBV) training is considered to improve pain and functional mobility effectively. However, few studies have investigated the therapeutic effect of WBV on neuromuscular function in KOA. MATERIAL AND

methodsA single-blinded, randomised, controlled trial was performed on 81 participants diagnosed with KOA. The participants were randomised into three groups: (1) WBV group, in which participants performed strength training (ST) with vibration exposure for 8 weeks; (2) ST group, in which participants performed ST without vibration for 8 weeks; and (3) health education (HE) group, in which participants received a HE for 8 weeks. The visual analogue scale for knee pain, isokinetic muscle strength test, proprioception test, Timed Up and Go test (TUG) and 6-min Walk Distance test (6MWD) were performed before and after the interventions.

resultsNo significant difference was found on pain, proprioception, TUG and 6MWD. A significant interaction effect was found in isokinetic muscle strength between groups. Further analysis showed that compared with the HE group, the WBV group exhibited significantly greater improvement in isokinetic muscle strength (peak torque [PT] of extensors, p < 0.01, 95% CI = 0.11-0.33 Nm/kg; PT of flexors, p = 0.01, 95% CI = 0.02-0.19 Nm/kg; peak work [PW] of extensors, p < 0.01, 95% CI = 0.12-0.75 W/kg). In addition, compared with the ST group, the muscle strength of the WBV group (PT of extensors, p < 0.01, 95% CI = 0.10-0.32 Nm/kg; PW of extensors, p < 0.01, 95% CI = 0.09-0.71 W/kg) improved significantly.

conclusionOur findings suggested that adding WBV training to ST might benefit muscle strength around the knee joint in patients with KOA.

Indexed as

KneeMuscle strengthPhysical therapyProprioception

Identifiers

PMID33680003
PMCPMC7895843
OpenAlexW3128821015

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.