Evidence map›Paper›PMID 33679767›Full record

ArticleFrontiers in immunology2021

Saisai Ren, Xiaorong Zhang, Hongbing Guan, Lihong Wu, Miao Yu, Dan Hou, Yongyong Yan, Xuechun Fang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. γδ T cells: origin and fate, subsets, diseases and immunotherapy.Signal transduction and targeted therapy · 2023
    Review
  10. Review
  11. Frontiers in immunology · 2022
    Review
  12. Review
  13. Intestinal Microbes of Hooded Cranes (Animals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Saisai RenGuangzhou Medical University, Guangzhou, China.
Xiaorong ZhangGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Hongbing GuanGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Lihong WuGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Miao YuGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Dan HouGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Yongyong YanGuangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Department of Basic Science of Stomatology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Xuechun FangGuangzhou Medical University, Guangzhou, China.
Guangzhou Medical University · CNStomatology Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis is a chronic autoimmune disease involving the central nervous system, and shows a high disability rate. Its pathogenesis is complicated, and there is no good treatment. In recent years, with in-depth studies on the regulation of gastrointestinal flora, the relationship between the mammalian immune system and the intestinal flora has been extensively explored. Changes in the composition and structure of the gastrointestinal flora can affect the characteristics and development of the host immune system and even induce a series of central nervous system inflammation events. The occurrence and development of multiple sclerosis are closely related to the continuous destruction of the intestinal barrier caused by intestinal dysbacteriosis. In this study, we analyzed

Indexed as

Gastrointestinal MicrobiomeProbioticsAnimalsCell DifferentiationCytokinesDisease Models, AnimalDysbiosisEncephalomyelitis, Autoimmune, ExperimentalFemaleGenes, T-Cell Receptor gammaHost-Pathogen InteractionsHyaluronan ReceptorsIntestinal MucosaIntraepithelial LymphocytesLactobacillusMiceCd44 protein, mouseCytokinesHyaluronan Receptorsexperimental autoimmune encephalomyelitisLactobacillus acidipiscismultiple sclerosisregulatory T cellsT helper cellsγδ T cells

Identifiers

PMID33679767
PMCPMC7933195
OpenAlexW3130344767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.