Evidence map›Paper›PMID 33679702›Full record

ArticleFrontiers in immunology2020

TLR7 Is Critical for Anti-Viral Humoral Immunity to EV71 Infection in the Spinal Cord.

Ya-Lin Lin, Mei-Yi Lu, Chi-Fen Chuang, Yali Kuo, Hong-En Lin, Fu-An Li, Jen-Ren Wang, Yi-Ping Hsueh, Fang Liao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  6. Article
  7. Current status of hand-foot-and-mouth disease.Journal of biomedical science · 2023
    Review
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ya-Lin LinInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Mei-Yi LuInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chi-Fen ChuangInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yali KuoInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Hong-En LinInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Fu-An LiInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Jen-Ren WangNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan, Taiwan.
Yi-Ping HsuehInstitute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Fang LiaoInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Institute of Biomedical Sciences, Academia Sinica · TWInstitute of Molecular Biology, Academia Sinica · TWNational Cheng Kung University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus 71 (EV71) is a positive single-stranded RNA (ssRNA) virus from the enterovirus genus of

Indexed as

Immunity, HumoralAnimalsAstrocytesB-LymphocytesCytokinesEnterovirus A, HumanEnterovirus InfectionsGerminal CenterImmunoglobulin GImmunoglobulin MMiceMice, Inbred C57BLMice, KnockoutMicrogliaMotor NeuronsOligodendrogliaCytokinesImmunoglobulin GImmunoglobulin MProteomeReceptors, IgGToll-Like Receptor 7antibodyEV71humoral immunityspinal cordTLR7

Identifiers

PMID33679702
PMCPMC7935532
OpenAlexW3130337240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.