Evidence map›Paper›PMID 33679615›Full record

ArticleFrontiers in endocrinology2021

A Comparison of the Efficacy of Immediate

Zhuo Liu, Fengyi Dong, Yunhan Wang, Mingming Zheng, Mengyang Song, Yixuan Wang, Jingyan Song

Open access · goldAbstract readComparative StudyClinical Trial Protocol
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Analysis of Relevant Factors Affecting the Pregnancy Rate of Frozen-Thawed Embryo Transfer Cycle.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhuo LiuReproductive and Genetic Center of Integrated Traditional and Western Medicine, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Fengyi DongChild Rehabilitation Center, Jinan Maternity and Child Care Hospital, Jinan, China.
Yunhan WangThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Mingming ZhengThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Mengyang SongThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Yixuan WangThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Jingyan SongThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Shandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Liaoning University of Traditional Chinese Medicine · CNJinan Maternity And Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In clinical practice, the ideal time at which to perform a Frozen-thawed Embryo Transfer (FET) after a failed Methods/analysis: The study is a randomized, non-inferiority, parallel-group, controlled trial that will enroll a total of 732 women undergoing their first FET after a failed fresh embryo transfer (ET) cycle. The participants will then be randomized into two groups based on a computer-generated randomized list. The two groups include: (i) an immediate group were FET will be carried out during the first menstrual cycle after a failed fresh ET cycle and (ii) a delayed group where FET will be carried out during the second menstrual cycle after a failed fresh ET cycle. Primary outcomes will be defined as viable pregnancies with fetal heartbeats, diagnosed through pelvic ultrasonography after twelve weeks of gestation. Ethics and dissemination: The study was approved by the Ethics Committee of the Assisted Reproductive Medicine at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine (SDTCM/E-2020.2.01). In addition, written informed consent will be obtained from all the participants before the study. The results of this trial will be disseminated in a peer-reviewed journal. Discussion: Currently, there is no consensus with regard to the duration after which the effects of ovarian stimulation are observed after a failed fresh ET and the optimal time required to begin FET. Moreover, no randomized controlled trial exists that compares the ongoing pregnancy rates after immediate versus delayed FET following a failed fresh ET cycle. Therefore, it is important to conduct a well-designed randomized trial to determine whether it is necessary to delay FET for at least one menstrual cycle after the failure of fresh ET. Clinical Trial Registration: ChiCTR2000033313 (http://www.chictr.org.cn/enIndex.aspx).

Indexed as

Pregnancy RateAdultBlastocystChinaEmbryo TransferEquivalence Trials as TopicFemaleFertilization in VitroFreezingHumansOvulation InductionPregnancyRandomized Controlled Trials as TopicSalvage TherapySpecimen HandlingTime Factorsfrozen–thawed embryo transferin-vitro fertilizationpregnancyrandomized controlled trialtime interval

Identifiers

PMID33679615
PMCPMC7931811
OpenAlexW3132980932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.