Evidence map›Paper›PMID 33679594›Full record

ReviewFrontiers in neurology2021

Vestibular Thresholds: A Review of Advances and Challenges in Clinical Applications.

Megan J Kobel, Andrew R Wagner, Daniel M Merfeld, Jameson K Mattingly

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06732440 (Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06732440 narecruitingnot on this mapstarted 2026, after this paper: background citation

Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation

TypeinterventionalSponsorCreighton UniversityRan2026 to 2026Enrolled48ConditionsVestibular Hypofunction, Bilateral Vestibular Hypofunction, Presbyvestibulopathy, Healthy ControlsArmsSubthreshold Vestibular Conditioning, Balance Training, Balance Training Plus Subthreshold Conditioning
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  8. Review
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  12. Review
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  14. Article
  15. Intra-individual consistency of vestibular perceptual thresholds.Attention, perception & psychophysics · 2024
    Article
  16. Review
  17. Article
  18. Psychometrics of inertial heading perception.Journal of vestibular research : equilibrium & orientation · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Megan J KobelDepartment of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Andrew R WagnerDepartment of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Daniel M MerfeldDepartment of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Jameson K MattinglyDepartment of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
The Ohio State University · USThe Ohio State University Wexner Medical Center · US

Funding

Employing Vestibular Thresholds to Improve Patient DiagnosisR01DC014924 · NIDCD · OHIO STATE UNIVERSITY · PI LEWIS, RICHARD F, MERFELD, DANIEL M · 2015 to 2019
$2.7M
NIDCD NIH HHS R01 DC014924
6 · The paper itself

Abstract

Vestibular disorders pose a substantial burden on the healthcare system due to a high prevalence and the severity of symptoms. Currently, a large portion of patients experiencing vestibular symptoms receive an ambiguous diagnosis or one that is based solely on history, unconfirmed by any objective measures. As patients primarily experience perceptual symptoms (e.g., dizziness), recent studies have investigated the use of vestibular perceptual thresholds, a quantitative measure of vestibular perception, in clinical populations. This review provides an overview of vestibular perceptual thresholds and the current literature assessing use in clinical populations as a potential diagnostic tool. Patients with peripheral and central vestibular pathologies, including bilateral vestibulopathy and vestibular migraine, show characteristic changes in vestibular thresholds. Vestibular perceptual thresholds have also been found to detect subtle, sub-clinical declines in vestibular function in asymptomatic older adults, suggesting a potential use of vestibular thresholds to augment or complement existing diagnostic methods in multiple populations. Vestibular thresholds are a reliable, sensitive, and specific assay of vestibular precision, however, continued research is needed to better understand the possible applications and limitations, especially with regard to the diagnosis of vestibular disorders.

Indexed as

psychophysicsself-motion perceptionvestibular disordersvestibular systemvestibular thresholds

Identifiers

PMID33679594
PMCPMC7933227
OpenAlexW3129483746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.