Evidence map›Paper›PMID 33679428›Full record

ReviewFrontiers in physiology2021

Pathogenesis of Acute Kidney Injury in Coronavirus Disease 2019.

Jing-Yi Qian, Bin Wang, Lin-Li Lv, Bi-Cheng Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. COVID-19 associated acute kidney injury.Infectious diseases & immunity · 2025
    Review
  3. The PI3K/Akt pathway: a target for curcumin's therapeutic effects.Journal of diabetes and metabolic disorders · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. SARS-CoV-2 viral protein ORF3A injures renal tubules by interacting with TRIM59 to induce STAT3 activation.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Acute Kidney Injury Incidence, Stage, and Recovery in Patients with COVID-19.International journal of nephrology and renovascular disease · 2022
    Article
  13. [Kidney damage in COVID-19].Nephrologie & therapeutique · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing-Yi QianInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Bin WangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Lin-Li LvInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Bi-Cheng LiuInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Zhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the outbreak of Coronavirus Disease 2019 (COVID-19) in Wuhan, China, in December of 2019, it has rapidly become a global pandemic. Although acute respiratory disorder is the main manifestation of COVID-19, acute kidney injury (AKI) is another important extrapulmonary complication, which has a critical impact on the prognosis and mortality of patients. Current understanding about the exact pathogenesis of AKI in COVID-19 is unclear. Several studies have suggested that intrarenal, pre-renal and post-renal factors mediated collaboratively by direct virus attack, overloaded immune responses, drugs, sepsis, coagulation dysfunction, and underlying diseases may all be involved in the pathogenesis of AKI. This article reviews the current understanding of the pathogenesis of AKI in COVID-19.

Indexed as

ACE2acute kidney injurycoronavirus disease 2019mechanismSARS-CoV-2

Identifiers

PMID33679428
PMCPMC7928360
OpenAlexW3130115961

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.