Evidence map›Paper›PMID 33679420›Full record

ArticleFrontiers in pharmacology2021

Identification of Plasma hsa_circ_0005397 and Combined With Serum AFP, AFP-L3 as Potential Biomarkers for Hepatocellular Carcinoma.

Ruoyu Liu, Yi Li, Anqi Wu, Mingzhu Kong, Weijia Ding, Zeyang Hu, Lin Chen, Weihua Cai, Feng Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. NAT10-Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Identification ofEndocrine, metabolic & immune disorders drug targets · 2026
    Article
  11. Targeting collagen to optimize cancer immunotherapy.Experimental hematology & oncology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Hepatitis B virus-induced hepatocellular carcinoma: a persistent global problem.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ruoyu LiuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Jiangsu, China.
Yi LiDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Jiangsu, China.
Anqi WuDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Jiangsu, China.
Mingzhu KongDepartment of Laboratory Medicine, School of Public Health, Nantong University, Jiangsu, China.
Weijia DingDepartment of Laboratory Medicine, School of Public Health, Nantong University, Jiangsu, China.
Zeyang HuDepartment of Laboratory Medicine, School of Public Health, Nantong University, Jiangsu, China.
Lin ChenDepartment of Gastroenterology and Laboratory Medicine, Nantong Third Hospital Affiliated to Nantong University, Jiangsu, China.
Weihua CaiDepartment of Gastroenterology and Laboratory Medicine, Nantong Third Hospital Affiliated to Nantong University, Jiangsu, China.
Feng WangDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Jiangsu, China.
Nantong University · CNAffiliated Hospital of Nantong University · CNWuxi Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha-fetoproteinbiomarkercircular RNAhepatocellular carcinomahsa_circ_0005397

Identifiers

PMID33679420
PMCPMC7933497
OpenAlexW3131202131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.