Evidence map›Paper›PMID 33679355›Full record

ArticleFrontiers in human neuroscience2021

No Impact of Stochastic Galvanic Vestibular Stimulation on Arterial Pressure and Heart Rate Variability in the Elderly Population.

Akiyoshi Matsugi, Koji Nagino, Tomoyuki Shiozaki, Yohei Okada, Nobuhiko Mori, Junji Nakamura, Shinya Douchi, Kosuke Oku, Kiyoshi Nagano, Yoshiki Tamaru

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07715227 (Effects of Galvanic Vestibular Stimulation on Heart Rate Variability), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07715227 nacompletednot on this map

Effects of Galvanic Vestibular Stimulation on Heart Rate Variability

TypeinterventionalSponsorAl-Farabi Kazakh National UniversityRan2021 to 2022Enrolled56ConditionsHealthy VolunteersArmsGalvanic Vestibular Stimulation (GVS) using BrainPatch device
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of continuous supplementation ofFrontiers in cardiovascular medicine · 2024
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Akiyoshi MatsugiFaculty of Rehabilitation, Shijonawate Gakuen University, Osaka, Japan.
Koji NaginoFaculty of Allied Health Sciences, Kansai University of Welfare Sciences, Osaka, Japan.
Tomoyuki ShiozakiDepartment of Otolaryngology-Head and Neck Surgery, Nara Medical University, Nara, Japan.
Yohei OkadaFaculty of Health Science, Kio University, Nara, Japan.
Nobuhiko MoriDepartment of Neuromodulation and Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Junji NakamuraFaculty of Health Science, Kio University, Nara, Japan.
Shinya DouchiDepartment of Rehabilitation, National Hospital Organization Wakayama Hospital, Wakayama, Japan.
Kosuke OkuFaculty of Rehabilitation, Kawasaki University of Medical Welfare, Okayama, Japan.
Kiyoshi NaganoFaculty of Rehabilitation, Shijonawate Gakuen University, Osaka, Japan.
Yoshiki TamaruFaculty of Rehabilitation, Shijonawate Gakuen University, Osaka, Japan.
Shijonawate Gakuen University · JPKio University · JPKansai University of Welfare Sciences · JPKawasaki University of Medical Welfare · JPNara Medical University · JPNational Hospital Organization · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNoisy galvanic vestibular stimulation (nGVS) is often used to improve postural stability in disorders, such as neurorehabilitation montage. For the safe use of nGVS, we investigated whether arterial pressure (AP) and heart rate vary during static supine and slow whole-body tilt with random nGVS (0.4 mA, 0.1-640 Hz, gaussian distribution) in a healthy elderly population.

methodsThis study was conducted with a double-blind, sham-controlled, cross-over design. Seventeen healthy older adults were recruited. They were asked to maintain a static supine position on a bed for 10 min, and the bed was tilted up (TU) to 70 degrees within 30 s. After maintaining this position for 3 min, the bed was passively tilted down (TD) within 30 s. Real-nGVS or sham-nGVS was applied from 4 to 15 min. The time course of mean arterial pressure (MAP) and RR interval variability (RRIV) were analyzed to estimate the autonomic nervous activity.

resultnGVS and/or time, including pre-/post-event (nGVS-start, TU, and TD), had no impact on MAP and RRIV-related parameters. Further, there was no evidence supporting the argument that nGVS induces pain, vertigo/dizziness, and uncomfortable feeling.

conclusionnGVS may not affect the AP and RRIV during static position and whole-body tilting or cause pain, vertigo/dizziness, and discomfort in the elderly.

Indexed as

arterial pressuregalvanic vestibular stimulationheart rate variabilityRR interval variabilitystochastic resonancewhole-body tilting

Identifiers

PMID33679355
PMCPMC7925407
OpenAlexW3133026722

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.