Evidence map›Paper›PMID 33679139›Full record

ArticleInternational journal of general medicine2021

Pulmonary Benign Ground-Glass Nodules: CT Features and Pathological Findings.

Wang-Jia Li, Fa-Jin Lv, Yi-Wen Tan, Bin-Jie Fu, Zhi-Gang Chu

Abstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Quantitative parameters of HRCT target scan to predict the risk of lung adenocarcinoma based on the detection of lung ground-glass nodules.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wang-Jia Li *Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0000-0002-8633-0101
Fa-Jin Lv *Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Yi-Wen TanDepartment of Pathology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Bin-Jie FuDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0000-0002-6863-2827
Zhi-Gang ChuDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0000-0002-2441-8132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome pulmonary ground-glass nodules (GGNs) are benign and frequently misdiagnosed due to lack of understanding of their CT characteristics. This study aimed to reveal the CT features and corresponding pathological findings of pulmonary benign GGNs to help improve diagnostic accuracy. PATIENTS AND

methodsFrom March 2016 to October 2019, patients with benign GGNs confirmed by operation or follow-up were enrolled retrospectively. According to overall CT manifestations, GGNs were classified into three types: I, GGO with internal high-attenuation zone; II, nodules lying on adjacent blood vessels; and other type, lesions without obvious common characteristics. CT features and pathological findings of each nodule type were evaluated.

resultsAmong the 40 type I, 25 type II, and 14 other type GGNs, 24 (60.0%), 19 (76.0%), and 10 (71.4%) nodules were resected, respectively. Type I GGNs were usually irregular (25 of 40, 62.5%) with only one high-attenuation zone (38 of 40, 95.0%) (main pathological components: thickened alveolar walls with inflammatory cells, fibrous tissue, and exudation), which was usually centric (24 of 40, 60.0%), having blurred margin (38 of 40, 95.0%), and connecting to blood vessels (32 of 40, 80.0%). The peripheral GGO (main pathological component: a small amount of inflammatory cell infiltration with fibrous tissue proliferation) was usually ill-defined (28 of 40, 70.0%). Type II GGNs (main pathological components: focal interstitial fibrosis with or without inflammatory cell infiltration) lying on adjacent vessel branches were usually irregular (19 of 25, 76.0%) and well defined (16 of 25, 64.0%) but showed coarse margins (15 of 16, 93.8%). Other type GGNs had various CT manifestations but their pathological findings were similar to that of type II.

conclusionFor subsolid nodules with CT features manifested in type I or II GGNs, follow-up should be firstly considered in further management.

Indexed as

benignityCTground-glass nodulelungpathology

Identifiers

PMID33679139
PMCPMC7930605

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