Evidence map›Paper›PMID 33679106›Full record

ArticleThe Saudi dental journal2021

The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia.

Ziyad AlHammad, Ihab Suliman, Sami Alotaibi, Hourya Alnofaie, Waad Alsaadi, Sarah Alhusseini, Ghadah Aldakheel, Noura Alsubaie

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Saudi dental journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Clinical and Descriptive Study of Orofacial Clefts in Colombia: 2069 Patients From Operation Smile Foundation.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ziyad AlHammadSaudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia.
Ihab SulimanDepartment of Cardiac Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Sami AlotaibiSaudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia.
Hourya AlnofaieSaudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia.
Waad AlsaadiPediatric Dentistry and Orthodontic Department, King Saud University, Riyadh, Saudi Arabia.
Sarah AlhusseiniCollege of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Ghadah AldakheelCollege of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Noura AlsubaieCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
King Saud bin Abdulaziz University for Health Sciences · SASaudi Commission for Health Specialties · SAKing Abdulaziz Medical City · SAKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrofacial clefts are considered one of the most common birth defects and are frequently associated with other malformations. Congenital heart disease is one of the most prevalent congenital malformation.

objectiveTo investigate the prevalence of congenital heart diseases associated with non-syndromic orofacial clefts in the Saudi population.

methodsElectronic files of non-syndromic orofacial cleft patients who visited the Oral and Maxillofacial Surgery Department in King Abdulaziz Medical City of Riyadh, Saudi Arabia from January 2015 to December 2018 were retrospectively reviewed. Data were recorded in an excel sheet and analyzed using SPSS via frequency tests.

resultsIn the cleft children identified, the prevalence of non-syndromic orofacial clefts was (77%). Orofacial clefts showed a male predominance (62%). The most common orofacial phenotype was unilateral cleft lip and palate (34%). The prevalence of associated congenital malformations with orofacial clefts was (41%). The most prevalent congenital malformation was congenital heart disease (35%), mainly found in unilateral cleft lip and palate patients (33%). The prevalence of associated congenital heart disease with orofacial clefts was (19%). The most frequent type of congenital heart disease was atrial septal defect (37%).

conclusionThis study highlights the recognition of the associated congenital heart disease with non-syndromic orofacial cleft patients. Global screening protocols designed for newborns with non-syndromic orofacial cleft are needed to eliminate late diagnosis of critical congenital heart diseases which might present operative risks of anesthesia and/or surgical procedures.

Indexed as

ASD, atrial septal defectAVS, aortic valve stenosisCHD, congenital heart diseaseCL, cleft lipCleft lip and palateCLP, cleft lip and palateCongenital heart diseaseCP, cleft palateMVP, mitral valve prolapseNon-syndromicOFC, orofacial cleftOrofacial cleftPrevalencePVS, pulmonary valve stenosisSaudi ArabiaTGA, transposition of great arteriesVSD, ventricular septal defect

Identifiers

PMID33679106
PMCPMC7910677
OpenAlexW2995009636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.