Evidence map›Paper›PMID 33679052›Full record

ArticleJournal of clinical and experimental hepatology

Granulomatous Tubercular Hepatitis Presenting as Secondary Hemophagocytic Lymphohistiocytosis: A Case Report and Systematic Review of the Literature.

Anshuman Elhence, Abhinav Aggarwal, Ashish Goel, Mukul Aggarwal, Prasenjit Das, Shalimar

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Hepatic Tuberculosis: A Wolf in Sheep's Clothing.Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anshuman ElhenceDepartment of Gastroenetrology, All India Institute of Medical Sciences, New Delhi, India.
Abhinav AggarwalDepartment of Medicine, University College of Medical Sciences, India.
Ashish GoelDepartment of Medicine, University College of Medical Sciences, India.
Mukul AggarwalDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Prasenjit DasDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
ShalimarDepartment of Gastroenetrology, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis is a life-threatening disorder characterized by persistent pathologic activation of cytotoxic T lymphocytes, natural killer cells, and macrophages. We present details of a young patient who presented with high-grade fever, jaundice, and breathlessness. On investigations, he had hepatitis, anemia, neutropenia, and coagulopathy. He also had hypertriglyceridemia, hypofibrinogenemia, and hyperferritinemia. Bone marrow aspiration revealed histiocytosis, and transjugular liver biopsy revealed necrotizing granulomas positive for

Indexed as

ADA, adenosine deaminaseAFB, acid-fast bacilliALP, alkaline phosphataseALT, alanine aminotransferaseAST, aspartate aminotransferaseATT, antitubercular therapyCAM, complementary and alternative medicineCMV, cytomegalovirusCRP, C-reactive proteinCTL, cytotoxic T lymphocyteEBV, Epstein-Barr virushemophagocytic lymphohistiocytosisHIV, human immunodeficiency virusHLHHLH, hemophagocytic lymphohistiocytosisHSV, herpes simplex virusINR, international normalized ratioLDH, lactate dehydrogenaselymph nodeNK cell, natural killer cellPTH, parathyroid hormonePUOSAAG, serum-ascites albumin gradientTB-HLH, tuberculosis-associated hemophagocytic lymphohistiocytosisTJLB, transjugular liver biopsytuberculosis

Identifiers

PMID33679052
PMCPMC7897858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.