Evidence map›Paper›PMID 33678746›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Diagnostic Utility of Polymerase Chain Reaction for Paraffin-embedded Sinus Specimens for Rhinocerebral Mucormycosis Complicated by Internal Carotid Artery Thrombosis and Cerebral Infarction.

Yukiko Maeda, Kunio Toda, Sono Toi, Tetsundo Yano, Mutsumi Iijima, Yuko Shimizu, Yoji Nagashima, Yasutomo Itakura, Shigekazu Iguchi, Ken Kikuchi and 3 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yukiko MaedaDepartment of Neurology, Tokyo Women's Medical University, Japan.
Kunio TodaDepartment of Neurology, Tokyo Women's Medical University, Japan.
Sono ToiDepartment of Neurology, Tokyo Women's Medical University, Japan.
Tetsundo YanoDepartment of Neurology, Tokyo Women's Medical University, Japan.
Mutsumi IijimaDepartment of Neurology, Tokyo Women's Medical University, Japan.
Yuko ShimizuDepartment of Neurology, Tokyo Women's Medical University, Japan.
Yoji NagashimaDepartment of Surgical Pathology, Tokyo Women's Medical University, Japan.
Yasutomo ItakuraDepartment of Infectious Diseases, Tokyo Women's Medical University, Japan.
Shigekazu IguchiDepartment of Infectious Diseases, Tokyo Women's Medical University, Japan.
Ken KikuchiDepartment of Infectious Diseases, Tokyo Women's Medical University, Japan.
Kazutoshi ShibuyaDepartment of Surgical Pathology Toho University, Japan.
Manabu NonakaDepartment of Otolaryngology, Tokyo Women's Medical University, Japan.
Kazuo KitagawaDepartment of Neurology, Tokyo Women's Medical University, Japan.
Tokyo Women's Medical University · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 73-year-old man who experienced cerebral infarction caused by infection with a Mucromycocetes species. A delay in anti-fungal treatment might result in a lethal clinical outcome. We were unable to establish an accurate diagnosis based on histological findings and cerebrospinal fluid culture. Therefore, we performed polymerase chain reaction (PCR) using paraffin-embedded specimens, and based on the findings, successfully started administering anti-fungal treatment. We suggest that PCR using sinus specimens be applied when mucormycosis is suspected as an etiology of cerebral infarction and a confirmative diagnosis cannot be established based on the results of pathological examinations or cerebrospinal fluid culture.

Indexed as

Carotid Artery ThrombosisMucormycosisAgedCerebral InfarctionHumansMaleParaffin EmbeddingPolymerase Chain Reactioncerebral ischemiaformalin-fixed paraffin-embedded specimensmucormycosisPCRsinusitis

Identifiers

PMID33678746
PMCPMC8429304
OpenAlexW3133781286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.