Evidence map›Paper›PMID 33678742›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Ramucirumab-related Oral Pyogenic Granuloma: A Report of Two Cases.

Tadanobu Aragaki, Nobuyoshi Tomomatsu, Yasuyuki Michi, Hisashi Hosaka, Yasuyuki Fukai, Misa Iijima, Tetsuya Yoda

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Oral Pyogenic Granuloma: A Narrative Review.International journal of molecular sciences · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tadanobu AragakiSection of Dentistry and Oral Surgery, Gunma Prefectural Cancer Center, Japan.
Nobuyoshi TomomatsuDepartment of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Yasuyuki MichiDepartment of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Hisashi HosakaSection of Gastroenterology, Gunma Prefectural Cancer Center, Japan.
Yasuyuki FukaiSection of Gastrointestinal Surgery, Gunma Prefectural Cancer Center, Japan.
Misa IijimaSection of Pathology, Gunma Prefectural Cancer Center, Japan.
Tetsuya YodaDepartment of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyogenic granuloma (PG) is a granulomatous elevated lesion that occurs on the skin and mucous membranes. We herein report two cases of intra-oral PG that developed during the administration of ramucirumab for gastric cancer. Case 1 involved a 55-year-old man with a 6-mm tumor on the right tongue, and case 2 involved a 67-year-old man with a 5-mm tumor on the upper lip. The imbalance in angiogenesis caused by ramucirumab and the deterioration in the local oral environment were suggested to have caused the PG. Medical and dental collaboration is essential during the administration of ramucirumab.

Indexed as

Granuloma, PyogenicAgedAntibodies, Monoclonal, HumanizedHumansLipMaleMiddle AgedMouth MucosaRamucirumabAntibodies, Monoclonal, HumanizedRamucirumabmedical and dental collaborationoral managementpyogenic granulomaramucirumabVEGFR2

Identifiers

PMID33678742
PMCPMC8429295
OpenAlexW3134206955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.