Evidence map›Paper›PMID 33678737›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Tumor Cells Detected in Retrieved Thrombus: Cancer-associated Stroke.

Kaoru Nakanishi, Hiroyuki Kawano, Yuki Yamagishi, Hiroshi Kamma, Yoshiaki Shiokawa, Teruyuki Hirano

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Mechanical thrombectomy for the treatment of large vessel occlusion due to cancer-related cerebral embolism: A systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Pooled it
  3. Cerebrovascular and Peripheral Vascular Complications in Cancer Patients.Current neurology and neuroscience reports · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kaoru NakanishiDepartment of Stroke and Cerebrovascular Medicine, Kyorin University, Japan.
Hiroyuki KawanoDepartment of Stroke and Cerebrovascular Medicine, Kyorin University, Japan.
Yuki YamagishiDepartment of Neurosurgery, Kyorin University, Japan.
Hiroshi KammaDepartment of Pathology, Kyorin University, Japan.
Yoshiaki ShiokawaDepartment of Neurosurgery, Kyorin University, Japan.
Teruyuki HiranoDepartment of Stroke and Cerebrovascular Medicine, Kyorin University, Japan.
Kyorin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 51-year-old man with a history of renal cell carcinoma presented with sudden aphasia, right hemiparesis, and dysesthesia. MRA showed left middle cerebral artery occlusion, and he was diagnosed with acute ischemic stroke and treated with intravenous recombinant tissue plasminogen activator and endovascular thrombectomy. The pathological diagnosis of the retrieved thrombus was consistent with the already-known pathological findings of the primary renal cell carcinoma. Therefore, a diagnosis of cerebral embolism caused by tumor cells was made. The pathological findings of the retrieved thrombi were important in determining the cause of ischemic stroke.

Indexed as

Brain IschemiaNeoplasmsStrokeThrombosisHumansInfarction, Middle Cerebral ArteryMaleMiddle AgedThrombectomyTissue Plasminogen ActivatorTreatment OutcomeTissue Plasminogen Activatorcancercerebral infarctionthrombectomythrombus

Identifiers

PMID33678737
PMCPMC8381188
OpenAlexW3135561547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.