Evidence map›Paper›PMID 33678652›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2021

Clinical characteristics of pulmonary alveolar proteinosis.

Yingjiao Long, Guiqian Liu, Hong Peng, Yan Chen, Ping Chen, Ruoyun Ouyang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yingjiao LongDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China. longyingjiao@163.com.
Guiqian LiuDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China.
Hong PengDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China.
Yan ChenDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China.
Ping ChenDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China.
Ruoyun OuyangDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital; Research Unit of Respiratory Disease, Central South University; Respiratory Disease Diagnosis and Treatment Center of Hunan Province, Changsha 410011, China. ouyangruoyun@csu.edu.cn.
Central South University · CN

Funding

the National Key Clinical Specialty Construction Project 2012-650the National Key Research and Development Program 2016YFC0901502the National Natural Science Foundation 81800043
6 · The paper itself

Abstract

objectivesPulmonary alveolar proteinosis (PAP) is a rare disease with non-specific and various clinical manifestations, often leading to misdiagnosis. This study aims to raise the awareness of this disease via summarizing the clinical characteristics, diagnosis, and therapy of PAP.

methodsWe retrospectively analyzed clinical data of 25 hospitalized cases of PAP during 2008 and 2019 in the Department of Respiratory and Critical Care Medicine of the Second Xiangya Hospital of Central South University.

resultsCough with unkown reason and dyspnea were common clinical manifastations of PAP. Five patients had a history of occupational inhalational exposure. Sixteen patients had typical image features including ground-glass opacification of alveolar spaces and thickening of the interlobular and intralobular septa, in typical shapes called crazy-paving and geographic pattern. Fourteen patients underwent pulmonary function tests, revealing a reduction in the diffusing capacity for carbon monoxide. The positive rate of transbronchial biopsy was 95%. Five patients received the whole lung lavage and the symptoms and imaging fcauters significantly relieved after five-years follow-up.

conclusionsPAP is characterized by radiographic pattern and pathology. Transbronchial lung biopsy is effective to make diagnosis of PAP. The whole lung lavage remains a efficient therapy.

Indexed as

Pulmonary Alveolar ProteinosisBiopsyBronchoalveolar LavageCoughDyspneaHumansRetrospective Studiesclinical characteristicimage featurespulmonary alveolar proteinosis

Identifiers

PMID33678652
PMCPMC10929776
OpenAlexW3135780543

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.