Evidence map›Paper›PMID 33678123›Full record

ArticlePharmaceutical biology2021

Protective effects of Re-yan-ning mixture on

Lizhu Han, Jing Kou, Kunxia Hu, Yunlan Wang, Zhishu Tang, Zhisheng Wu, Xiao Song

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lizhu HanCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Jing KouCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Kunxia HuCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Yunlan WangCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Zhishu TangCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Zhisheng WuCollege of Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Xiao SongCollege of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Shaanxi University of Chinese Medicine · CNBeijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextRe-yan-ning mixture (RYNM) is a new national drug approved by China's State Food and Drug Administration for the treatment of colds, simple pneumonia and acute bronchitis.

objectiveTo determine the mechanism of action of RYNM in the treatment of bacterial pneumonia. MATERIALS AND

methodsUsing the network pharmacology approach, the multiple components, component candidate targets and multiple therapeutic targets of RYNM were screened and functionally enriched. Also, we established a rat

resultsThe network pharmacology approach successfully identified 48 bioactive components in RYNM, and 65 potential targets and 138 signal pathways involved in the treatment of DISCUSSION AND

conclusionsThe present study demonstrated the protective effects of RYNM on

Indexed as

AnimalsDisease Models, AnimalDrugs, Chinese HerbalInflammationMaleNF-kappa BPneumonia, PneumococcalRatsRats, Sprague-DawleySignal TransductionStreptococcus pneumoniaeTumor Necrosis Factor-alphaDrugs, Chinese HerbalNF-kappa BTumor Necrosis Factor-alphapneumoniasignal pathwayTraditional Chinese medicine

Identifiers

PMID33678123
PMCPMC7939573
OpenAlexW3135723619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.